Browsing Toxins By Category
Displaying toxin 876 - 900 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3770 | Moniliformin 71376-34-6 | C4H2O3 98.057 g/mol |  |
| Moniliformin reversibly inhibits the enzymes pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase by competing for the binding site of pyruvate. This interfere...more Number of Targets: 7 |
| T3D3769 | Kojic acid 501-30-4 | C6H6O4 142.109 g/mol |  |
| Kojic acid acts as a competitive and reversible inhibitor of animal and plant polyphenol oxidases (tyrosinases), xanthine oxidase, and D- and some L-amino acid oxidase...more Number of Targets: 4 |
| T3D3768 | Luteoskyrin 21884-44-6 | C30H22O12 574.489 g/mol |  |
| Luteoskyrin is hepatotoxic. It is thought that this is a result of its metabolic reduction to the semiquinone radical catalyzed by NADPH-dependent cytochrome reductase...more Number of Targets: 26 |
| T3D3767 | Lolitrem B 81771-19-9 | C42H55NO7 685.889 g/mol |  |
| The neurological effects of Lolitrem B are a result of its ability to inhibit large conductance calcium-activated potassium channels (BK channels). Lolitrem B binds to...more Number of Targets: 1 |
| T3D3766 | Janthitrem G 90986-51-9 | C39H51NO6 629.825 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3765 | Janthitrem F 90986-52-0 | C39H51NO7 645.825 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3764 | Janthitrem E 90986-50-8 | C37H49NO6 603.788 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3763 | Janthitrem C 73561-91-8 | C37H47NO4 569.773 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3762 | Janthitrem B 73561-90-7 | C37H47NO5 585.773 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3760 | Fumagillin 23110-15-8 | C26H34O7 458.544 g/mol |  |
| Fumagillin blocks blood vessel formation (angiogenesis) by inhibiting the enzyme methionine aminopeptidase 2. This prevents angiogenesis by arresting endothelial cells...more Number of Targets: 1 |
| T3D3759 | Enniatin B1 19914-20-6 | C34H59N3O9 653.847 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3758 | Enniatin B 917-13-5 | C33H57N3O9 639.820 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3757 | Enniatin A1 4530-21-6 | C35H61N3O9 667.874 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3756 | Enniatin A 2503-13-1 | C36H63N3O9 681.900 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3755 | Emodin 518-82-1 | C15H10O5 270.237 g/mol |  |
| Emodin is moderately cytotoxic and can inhibit the growth of many cell types by interfering with the cell cycle, possibly by stimulating the expression of p53 and p21....more Number of Targets: 20 |
| T3D3754 | Emestrin 97816-62-1 | C27H22N2O10S2 598.601 g/mol |  |
| Emestrin causes degeneration of the mitochondria in both cardiac muscle cells and hepatocytes, leading to necrosis. It is also known to act as an antagonist at the che...more Number of Targets: 2 |
| T3D3753 | Butenolide 16275-44-8 | C6H7NO3 141.125 g/mol |  |
| Butenolide causes lipid peroxidation, disrupting the membrane lipid bilayer and causing damage to membrane protiens. It also induces production of reactive oxygen spec...more Number of Targets: 17 |
| T3D3752 | Arisugacin A 167114-89-8 | C24H24O8 440.443 g/mol |  |
| Arisugacin A is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 1 |
| T3D3751 | Aurovertin D 65256-31-7 | C25H32O9 476.516 g/mol |  |
| Aurovertins are a mixed, noncompetitive inhibitors of both ATP hydrolysis and synthesis. They do this by inhibiting the proton-pumping F1F0-ATP synthase by binding to ...more Number of Targets: 1 |
| T3D3750 | Aurovertin B 55350-03-3 | C25H32O8 460.517 g/mol |  |
| Aurovertins are a mixed, noncompetitive inhibitors of both ATP hydrolysis and synthesis. They do this by inhibiting the proton-pumping F1F0-ATP synthase by binding to ...more Number of Targets: 3 |
| T3D3749 | Asteltoxin 79663-49-3 | C23H30O7 418.480 g/mol |  |
| Asteltoxin inhibits mitochondrial respiration by affecting its energy transfer system. It does this by inhibiting Mg2+ and Na+/K+-ATPases. (A3002, A3003, A3031) Number of Targets: 8 |
| T3D3748 | Paspalinine 63722-91-8 | C27H31NO4 433.539 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D3747 | Territrem C 89020-33-7 | C28H32O9 512.548 g/mol |  |
| Territrem C is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 1 |
| T3D3746 | Territrem A 70407-19-1 | C28H30O9 510.532 g/mol |  |
| Territrem A is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 1 |
| T3D3745 | Territrem B 70407-20-4 | C29H34O9 526.575 g/mol |  |
| Territrem B is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 2 |