Browsing Toxins By Category
Displaying toxin 2326 - 2350 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0661 | Cobalt(II) iodide 15238-00-3 | CoI2 312.742 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1114 | Barium iron oxide 12047-11-9 | BaFe2O4 313.015 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D1354 | Phenylmercuric chloride 100-56-1 | C6H5ClHg 313.150 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 51 |
| T3D3047 | Flunitrazepam 1622-62-4 | C16H12FN3O3 313.283 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 21 |
| T3D2720 | Reboxetine 98769-81-4 | C19H23NO3 313.391 g/mol |  |
| Reboxetine is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake in vitro to a similar extent to the tricyclic antidepressant desmethy...more Number of Targets: 1 |
| T3D4517 | Isazofos 42509-80-8 | C9H17ClN3O3PS 313.741 g/mol |  |
| Isazofos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 16 |
| T3D2819 | Amoxapine 14028-44-5 | C17H16ClN3O 313.781 g/mol |  |
| Amoxapine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT). Number of Targets: 25 |
| T3D1616 | Silver sulfate 10294-26-5 | Ag2H2O4S 313.815 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D4514 | Hexaconazole 79983-71-4 | C14H17Cl2N3O 314.210 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D3669 | Aflatoxin B2 7220-81-7 | C17H14O6 314.290 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 3 |
| T3D3725 | Aflatoxicol 29611-03-8 | C17H14O6 314.290 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 1 |
| T3D4519 | Malaoxon 1634-78-2 | C10H19O7PS 314.292 g/mol |  |
| Malaoxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 9 |
| T3D4842 | Dibutyl decanedioate 109-43-3 | C18H34O4 314.460 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2801 | delta9-Tetrahydrocannabinol 1972-08-3 | C21H30O2 314.462 g/mol |  |
| The mechanism of action of marinol is not completely understood. It is thought that cannabinoid receptors in neural tissues may mediate the effects of dronabinol and o...more Number of Targets: 3 |
| T3D3011 | Pergolide 66104-22-1 | C19H26N2S 314.488 g/mol |  |
| The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi proteins. In lactotrophs, stimulation of dopamine D2 receptor causes inhibi...more Number of Targets: 17 |
| T3D0141 | S,S,S-Tributyl phosphorotrithioate 78-48-8 | C12H27OPS3 314.511 g/mol |  |
| S,S,S-Tributyl phosphorotrithioate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the ac...more Number of Targets: 17 |
| T3D1298 | Arsenic tribromide 7784-33-0 | AsBr3 314.634 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 50 |
| T3D2842 | Clorazepate 23887-31-2 | C16H11ClN2O3 314.723 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D3032 | Clomipramine 303-49-1 | C19H23ClN2 314.852 g/mol |  |
| Clomipramine is a strong, but not completely selective serotonin reuptake inhibitor (SRI), as the active main metabolite desmethyclomipramine acts preferably as an inh...more Number of Targets: 16 |
| T3D4023 | Neosaxitoxin 64296-20-4 | C10H17N7O5 315.286 g/mol |  |
| Neosaxitoxin (NSTX) blocks the extracellular portion, the outer vestibule, of some voltage gated sodium channels in a very powerful and reversible manner, without affe...more Number of Targets: 0 |
| T3D2809 | Oxycodone 76-42-6 | C18H21NO4 315.364 g/mol |  |
| Oxycodone acts as a weak agonist at mu, kappa, and delta opioid receptors within the central nervous system (CNS). Oxycodone primarily affects mu-type opioid receptors...more Number of Targets: 5 |
| T3D3850 | Flusilazole 85509-19-9 | C16H15F2N3Si 315.393 g/mol |  |
| Flusilazole has a dose-related inhibition of serum testosterone and estradiol concentrations in rats. This inhibition of testosterone and estradiol biosynthesis may di...more Number of Targets: 20 |
| T3D2973 | Clonazepam 1622-61-3 | C15H10ClN3O3 315.711 g/mol |  |
| Allosteric interactions between central benzodiazepine receptors and gamma-aminobutyric acid (GABA) receptors potentiate the effects of GABA. As GABA is an inhibitory ...more Number of Targets: 21 |
| T3D3031 | Chlorprothixene 113-59-7 | C18H18ClNS 315.860 g/mol |  |
| Chlorprothixene blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is bel...more Number of Targets: 16 |
| T3D2336 | Bromodichlorodibenzofuran 107227-60-1 | C12H5BrCl2O 315.977 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |