Browsing Toxins By Category
Displaying toxin 2301 - 2325 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4765 | Tolazamide 1156-19-0 | C14H21N3O3S 311.400 g/mol |  |
| Sulfonylureas likely bind to ATP-sensitive potassium-channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the...more Number of Targets: 3 |
| T3D3836 | Fenamidone 161326-34-7 | C17H17N3OS 311.401 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D2897 | Biperiden 514-65-8 | C21H29NO 311.461 g/mol |  |
| Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of...more Number of Targets: 5 |
| T3D1087 | Butachlor 23184-66-9 | C17H26ClNO2 311.847 g/mol |  |
| Binds to nAChRs in nervous systems. Also causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (T10, A590) Number of Targets: 35 |
| T3D1918 | 2,3-Dibromobiphenyl 115245-06-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1939 | 2,2'-Dibromobiphenyl 13029-09-9 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1941 | 3,5-Dibromobiphenyl 16372-96-6 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1943 | 3,3'-Dibromobiphenyl 16400-51-4 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1954 | 2,3'-Dibromobiphenyl 49602-90-6 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1955 | 2,4'-Dibromobiphenyl 49602-91-7 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1957 | 2,4-Dibromobiphenyl 53592-10-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1960 | 3,4'-Dibromobiphenyl 57186-90-0 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1961 | 2,5-Dibromobiphenyl 57422-77-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1962 | 2,6-Dibromobiphenyl 59080-32-9 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1977 | 3,4-Dibromobiphenyl 60108-72-7 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2019 | 4,4'-Dibromobiphenyl 92-86-4 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1818 | Diphenyl diselenide 1666-13-3 | C12H10Se2 312.130 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D3598 | Aflatoxin B1 1162-65-8 | C17H12O6 312.274 g/mol |  |
| Aflatoxin B1 requires epoxidation to aflatoxin B1 2,3-oxide for activation, which is performed by cytochome P-450 enzymes CYP1A2 and CYP3A4. It produces DNA damage, ge...more Number of Targets: 11 |
| T3D3674 | Nivalenol 23282-20-4 | C15H20O7 312.315 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D0195 | Benzyl butyl phthalate 85-68-7 | C19H20O4 312.360 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 11 |
| T3D3558 | Cellulose nitrate 9004-70-0 | C20H16N4 312.368 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D2754 | Olanzapine 132539-06-1 | C17H20N4S 312.433 g/mol |  |
| Olanzapine's antipsychotic activity is likely due to a combination of antagonism at D2 receptors in the mesolimbic pathway and 5HT2A receptors in the frontal cortex. A...more Number of Targets: 36 |
| T3D4749 | Levonorgestrel 797-63-7 | C21H28O2 312.446 g/mol |  |
| Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once boun...more Number of Targets: 7 |
| T3D0694 | Nickel iodide 13462-90-3 | I2Ni 312.502 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D4454 | Phytanic acid 14721-66-5 | C20H40O2 312.530 g/mol |  |
| Not Available Number of Targets: 4 |