Browsing Toxins By Category
Displaying toxin 2251 - 2275 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2212 | 1,4,6,8-Tetrachlorodibenzofuran 82911-58-8 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2213 | 1,4,7,8-Tetrachlorodibenzofuran 83704-29-4 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2442 | 1,2,4,9-Tetrachlorodibenzofuran 83704-24-9 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2443 | 1,2,6,9-Tetrachlorodibenzofuran 70648-18-9 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2444 | 1,2,8,9-Tetrachlorodibenzofuran 70648-22-5 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2445 | 1,3,4,9-Tetrachlorodibenzofuran 83704-28-3 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2446 | 1,4,6,9-Tetrachlorodibenzofuran 70648-19-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2447 | 2,3,4,9-Tetrachlorodibenzofuran 83704-33-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2233 | 2,3,4,6-Tetrachlorodibenzofuran 83704-30-7 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2236 | 2,3,4,7-Tetrachlorodibenzofuran 83704-31-8 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2237 | 2,3,4,8-Tetrachlorodibenzofuran 83704-32-9 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2239 | 2,3,6,7-Tetrachlorodibenzofuran 57117-39-2 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2240 | 2,3,6,8-Tetrachlorodibenzofuran 57117-37-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2247 | 2,4,6,7-Tetrachlorodibenzofuran 57117-38-1 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2248 | 2,4,6,8-Tetrachlorodibenzofuran 58802-19-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0207 | 2,3,7,8-Tetrachlorodibenzofuran 51207-31-9 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2279 | 3,4,6,7-Tetrachlorodibenzofuran 57117-40-5 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2985 | Sertraline 79617-96-2 | C17H17Cl2N 306.230 g/mol |  |
| The exact mechanism of action sertraline is not fully known, but the drug appears to selectively inhibit the reuptake of serotonin at the presynaptic membrane. This re...more Number of Targets: 9 |
| T3D1314 | Triphenylarsine 603-32-7 | C18H15As 306.233 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D2711 | Fluconazole 86386-73-4 | C13H12F2N6O 306.271 g/mol |  |
| Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fu...more Number of Targets: 4 |
| T3D3654 | Di-n-pentyl phthalate 131-18-0 | C18H26O4 306.397 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 9 |
| T3D1782 | Bromodeoxyuridine 59-14-3 | C9H11BrN2O5 307.098 g/mol |  |
| 5-bromodeoxyuridine acts on DNA. It induces a random DNA point mutation via base substitution. The base pair will change from an A-T to a G-C or from a G-C to an A-T a...more Number of Targets: 3 |
| T3D4352 | Glutathione 70-18-8 | C10H17N3O6S 307.323 g/mol |  |
| Glutathione (GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase. It is also important as a hydrophilic molecule that is...more Number of Targets: 42 |
| T3D2787 | Zolpidem 82626-48-0 | C19H21N3O 307.390 g/mol |  |
| Zolpidem modulates the alpha-subunit, known as the benzodiazepine receptor, within the GABAA receptor chloride channel macromolecular complex. Unlike the benzodiazepin...more Number of Targets: 7 |
| T3D2724 | Benzatropine 86-13-5 | C21H25NO 307.429 g/mol |  |
| Benztropine is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or neuronal) and the peripheral muscari...more Number of Targets: 3 |