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Displaying toxin 1676 - 1700 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D1356Mercurol
12002-19-6
C4H4Hg
252.660 g/mol
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  • Industrial/Workplace Toxin
  • Mercury Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more
Number of Targets: 50
T3D4540Thiacloprid
111988-49-9
C10H9ClN4S
252.723 g/mol
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  • Amide
  • Amine
  • Ether
  • Insecticide
  • Nitrile
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 5
T3D1785Bromoform
75-25-2
CHBr3
252.731 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Pollutant
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 0
T3D1606Silver hexafluorophosphate
26042-63-7
AgF6P
252.832 g/mol
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  • Fluoride Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Silver Compound
  • Synthetic Compound
Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more
Number of Targets: 17
T3D20481,3-Dichlorodibenzo-p-dioxin
50585-39-2
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20491,6-Dichlorodibenzo-p-dioxin
38178-38-0
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20502,3-Dichlorodibenzo-p-dioxin
29446-15-9
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20512,7-Dichlorodibenzo-p-dioxin
33857-26-0
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20522,8-Dichlorodibenzo-p-dioxin
38964-22-6
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20531,4-Dichlorodibenzo-p-dioxin
54536-19-5
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20541,2-Dichlorodibenzo-p-dioxin
54536-18-4
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20551,9-Dichlorodibenzo-p-dioxin
64560-13-0
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20561,8-Dichlorodibenzo-p-dioxin
82291-27-8
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D20571,7-Dichlorodibenzo-p-dioxin
82291-26-7
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D23297,8-Dichloro-2-dibenzofuranol
74423-77-1
C12H6Cl2O2
253.081 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D3813Clopyralid-olamine
57754-85-5
C8H10Cl2N2O3
253.083 g/mol
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  • Herbicide
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 10
T3D00403,3'-Dichlorobenzidine
91-94-1
C12H10Cl2N2
253.127 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
3,3’-Dichlorobenzidine's mechanism of toxicity derives mainly from the adduction of DNA by its metabolites. The formation of nitroso derivatives during metabolism, yie...more
Number of Targets: 50
T3D4162Neopterin
2009-64-5
C9H11N5O4
253.215 g/mol
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  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Uremic Toxin
Uremic toxins such as neopterin are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimula...more
Number of Targets: 3
T3D0924Asulam, sodium salt
2302-17-2
C8H10N2NaO4S
253.231 g/mol
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  • Amide
  • Amine
  • Carbamate
  • Ester
  • Ether
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Asulam, sodium salt is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylc...more
Number of Targets: 2
T3D1677Isobornyl thiocyanoacetate
115-31-1
C13H19NO2S
253.360 g/mol
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  • Cyanide Compound
  • Ester
  • Ether
  • Industrial/Workplace Toxin
  • Nitrile
  • Organic Compound
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D2862Tizanidine
51322-75-9
C9H8ClN5S
253.711 g/mol
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  • Adrenergic alpha-2 Receptor Agonist
  • Adrenergic alpha-Agonist
  • Amide
  • Amine
  • Analgesic
  • Anticonvulsant
  • Drug
  • Metabolite
  • Muscle Relaxant
  • Muscle Relaxant, Central
  • Muscle Relaxant, Skeletal
  • Neuromuscular Agent
  • Organic Compound
  • Organochloride
  • Parasympatholytic
  • Synthetic Compound
Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agonist action at a2-adrenergic receptor sites.
Number of Targets: 4
T3D1743Nitrogen tribromide
15162-90-0
Br3N
253.719 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Non-Metal
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D3596Iodine
7553-56-2
I2
253.809 g/mol
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  • Cosmetic Toxin
  • Disinfectant
  • Food Toxin
  • Halogen
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Non-Metal
Iodide inhibits adenylate cyclase in thyroid gland follicle cells and decreases the TSH-induced rise in intracellular cAMP. This results in decreased iodination of thy...more
Number of Targets: 10
T3D1902Tris(dimethylamino)antimony
7289-92-1
C6H18N3Sb
253.990 g/mol
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  • Amine
  • Antimony Compound
  • Food Toxin
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more
Number of Targets: 20
T3D1173Uranium carbide
12070-09-6
CH4U
254.071 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Radioactive
  • Synthetic Compound
  • Uranium Compound
Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more
Number of Targets: 1
Displaying toxin 1676 - 1700 of 3678 in total