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Displaying toxin 1626 - 1650 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D3835Etridiazole
2593-15-9
C5H5Cl3N2OS
247.530 g/mol
Thumb
  • Ether
  • Fungicide
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Not Available
Number of Targets: 3
T3D4513Forchlorfenuron
68157-60-8
C12H10ClN3O
247.680 g/mol
Thumb
  • Amine
  • Food Toxin
  • Organic Compound
  • Organochloride
  • Plant Growth Regulator
  • Synthetic Compound
Not Available
Number of Targets: 18
T3D4509Fludioxonil
131341-86-1
C12H6F2N2O2
248.185 g/mol
Thumb
  • Ether
  • Fungicide
  • Nitrile
  • Organic Compound
  • Organofluoride
  • Pesticide
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 19
T3D2482Dapsone
80-08-0
C12H12N2O2S
248.301 g/mol
Thumb
  • Amine
  • Anti-Infective Agent
  • Anti-Inflammatory Agent
  • Antimalarial
  • Antimycobacterial
  • Drug
  • Folic Acid Antagonist
  • Leprostatic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Dapsone acts against bacteria and protozoa in the same way as sulphonamides, that is by inhibiting the synthesis of dihydrofolic acid through competition with para-ami...more
Number of Targets: 3
T3D4081Matrine
519-02-8
C15H24N2O
248.364 g/mol
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  • Amide
  • Amine
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The nervous system is the main target organ by the toxicity of matrine. Morphological observation revealed degenerative changes of the nerve cells in the brain tissue ...more
Number of Targets: 0
T3D4779Pyrimethamine
58-14-0
C12H13ClN4
248.711 g/mol
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  • Amine
  • Antimalarial
  • Antiprotozoal Agent
  • Drug
  • Folic Acid Antagonist
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis a...more
Number of Targets: 10
T3D0684Nickel acetate
373-02-4
C4H14NiO8
248.843 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Nickel Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 68
T3D1259Dibutyltin oxide
818-08-6
C8H18OSn
248.940 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
  • Tin Compound
Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more
Number of Targets: 12
T3D08022,4-Dichlorophenoxybutyric acid
94-82-6
C10H10Cl2O3
249.091 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Ether
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Some of the endocrine effects of 2,4-DB may be mediated by the 2,4-D mediated displacement of sex hormones from the sex hormone binding globulin or the 2,4-D mediated ...more
Number of Targets: 9
T3D4518Linuron
330-55-2
C9H10Cl2N2O2
249.094 g/mol
Thumb
  • Herbicide
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Linuron is a weak competitive inhibitor of androgen receptor binding and it inhibits androgen-induced gene expression in vitro. This may partially contribute to the ma...more
Number of Targets: 9
T3D2666Alendronic acid
66376-36-1
C4H13NO7P2
249.096 g/mol
Thumb
  • Amine
  • Antihypocalcemic Agent
  • Antiresorptive
  • Bisphosphonate
  • Bone Density Conservation Agent
  • Drug
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The action of Alendronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Alendronate also targets farn...more
Number of Targets: 7
T3D20364-Bromobiphenyl Ether
101-55-3
C12H9BrO
249.103 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Pollutant
  • Polybrominated Biphenyl
  • Synthetic Compound
Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more
Number of Targets: 6
T3D09063-tert-Butylphenyl sec-butylcarbamate
97508-29-7
C15H23NO2
249.349 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Carbamate
  • Ester
  • Organic Compound
  • Pesticide
  • Synthetic Compound
3-tert-Butylphenyl sec-butylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamo...more
Number of Targets: 2
T3D3815Clothianidin
210880-92-5
C6H8ClN5O2S
249.678 g/mol
Thumb
  • Amine
  • Insecticide
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 8
T3D1413Dichlorobis(ethylenediamine)nickel(II)
22980-82-1
C4H16Cl2N4Ni
249.796 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Nickel Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 68
T3D2918Diflunisal
22494-42-4
C13H8F2O3
250.198 g/mol
Thumb
  • Anti-Inflammatory Agent, Non-Steroidal
  • Cyclooxygenase Inhibitor
  • Drug
  • Ester
  • Metabolite
  • Organic Compound
  • Organofluoride
  • Synthetic Compound
The precise mechanism of the analgesic and anti-inflammatory actions of diflunisal is not known. Diflunisal is a prostaglandin synthetase inhibitor. In animals, prosta...more
Number of Targets: 7
T3D3597Citrinin
518-75-2
C13H14O5
250.247 g/mol
Thumb
  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Citrinin produces proximal tubular necrosis, but only after transport into proximal tubular cells. It utilizes the organic anion transporter for entry into the cells, ...more
Number of Targets: 28
T3D1590Hydrogen tetrachloro-palladate(II)
16970-55-1
Cl4H2Pd
250.250 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Palladium Compound
  • Synthetic Compound
Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more
Number of Targets: 6
T3D1664Methylene diphenyl diisocyanate
101-68-8
C15H10N2O2
250.252 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cyanide Compound
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Pollutant
  • Synthetic Compound
  • Volatile Isocyanate
Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more
Number of Targets: 39
T3D3655Di-n-propyl phthalate
131-16-8
C14H18O4
250.290 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 8
T3D4809Gemfibrozil
25812-30-0
C15H22O3
250.333 g/mol
Thumb
  • Drug
  • Ether
  • Hypolipidemic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Gemfibrozil increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. It does so by activating Peroxisome ...more
Number of Targets: 2
T3D3717Trichodermol
2198-93-8
C15H22O3
250.333 g/mol
Thumb
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D1723Boron tribromide
10294-33-4
BBr3
250.523 g/mol
Thumb
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D0699Nickel sulfamate
13770-89-3
H4N2NiO6S2
250.865 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nickel Compound
  • Pollutant
  • Synthetic Compound
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 68
T3D0360Methylmercuric chloride
125-09-3
CH3ClHg
251.080 g/mol
Thumb
  • Mercury Compound
  • Organic Compound
  • Organometallic
  • Pesticide
  • Pollutant
  • Synthetic Compound
High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more
Number of Targets: 50
Displaying toxin 1626 - 1650 of 3678 in total