Browsing Toxins By Category
Displaying toxin 1626 - 1650 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3835 | Etridiazole 2593-15-9 | C5H5Cl3N2OS 247.530 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4513 | Forchlorfenuron 68157-60-8 | C12H10ClN3O 247.680 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D4509 | Fludioxonil 131341-86-1 | C12H6F2N2O2 248.185 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 19 |
| T3D2482 | Dapsone 80-08-0 | C12H12N2O2S 248.301 g/mol |  |
| Dapsone acts against bacteria and protozoa in the same way as sulphonamides, that is by inhibiting the synthesis of dihydrofolic acid through competition with para-ami...more Number of Targets: 3 |
| T3D4081 | Matrine 519-02-8 | C15H24N2O 248.364 g/mol |  |
| The nervous system is the main target organ by the toxicity of matrine. Morphological observation revealed degenerative changes of the nerve cells in the brain tissue ...more Number of Targets: 0 |
| T3D4779 | Pyrimethamine 58-14-0 | C12H13ClN4 248.711 g/mol |  |
| Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis a...more Number of Targets: 10 |
| T3D0684 | Nickel acetate 373-02-4 | C4H14NiO8 248.843 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D1259 | Dibutyltin oxide 818-08-6 | C8H18OSn 248.940 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D0802 | 2,4-Dichlorophenoxybutyric acid 94-82-6 | C10H10Cl2O3 249.091 g/mol |  |
| Some of the endocrine effects of 2,4-DB may be mediated by the 2,4-D mediated displacement of sex hormones from the sex hormone binding globulin or the 2,4-D mediated ...more Number of Targets: 9 |
| T3D4518 | Linuron 330-55-2 | C9H10Cl2N2O2 249.094 g/mol |  |
| Linuron is a weak competitive inhibitor of androgen receptor binding and it inhibits androgen-induced gene expression in vitro. This may partially contribute to the ma...more Number of Targets: 9 |
| T3D2666 | Alendronic acid 66376-36-1 | C4H13NO7P2 249.096 g/mol |  |
| The action of Alendronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Alendronate also targets farn...more Number of Targets: 7 |
| T3D2036 | 4-Bromobiphenyl Ether 101-55-3 | C12H9BrO 249.103 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 6 |
| T3D0906 | 3-tert-Butylphenyl sec-butylcarbamate 97508-29-7 | C15H23NO2 249.349 g/mol |  |
| 3-tert-Butylphenyl sec-butylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamo...more Number of Targets: 2 |
| T3D3815 | Clothianidin 210880-92-5 | C6H8ClN5O2S 249.678 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D1413 | Dichlorobis(ethylenediamine)nickel(II) 22980-82-1 | C4H16Cl2N4Ni 249.796 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D2918 | Diflunisal 22494-42-4 | C13H8F2O3 250.198 g/mol |  |
| The precise mechanism of the analgesic and anti-inflammatory actions of diflunisal is not known. Diflunisal is a prostaglandin synthetase inhibitor. In animals, prosta...more Number of Targets: 7 |
| T3D3597 | Citrinin 518-75-2 | C13H14O5 250.247 g/mol |  |
| Citrinin produces proximal tubular necrosis, but only after transport into proximal tubular cells. It utilizes the organic anion transporter for entry into the cells, ...more Number of Targets: 28 |
| T3D1590 | Hydrogen tetrachloro-palladate(II) 16970-55-1 | Cl4H2Pd 250.250 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1664 | Methylene diphenyl diisocyanate 101-68-8 | C15H10N2O2 250.252 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D3655 | Di-n-propyl phthalate 131-16-8 | C14H18O4 250.290 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 8 |
| T3D4809 | Gemfibrozil 25812-30-0 | C15H22O3 250.333 g/mol |  |
| Gemfibrozil increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. It does so by activating Peroxisome ...more Number of Targets: 2 |
| T3D3717 | Trichodermol 2198-93-8 | C15H22O3 250.333 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D1723 | Boron tribromide 10294-33-4 | BBr3 250.523 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0699 | Nickel sulfamate 13770-89-3 | H4N2NiO6S2 250.865 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D0360 | Methylmercuric chloride 125-09-3 | CH3ClHg 251.080 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |