Browsing Toxins By Category
Displaying toxin 1576 - 1600 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3817 | Cyanazine 21725-46-2 | C9H13ClN6 240.693 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 13 |
| T3D0668 | Cobalt(II, III) oxide 1308-06-1 | Co3O4 240.797 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1422 | Nickel potassium cyanide 14220-17-8 | C4K2N4Ni 240.960 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 110 |
| T3D0129 | Americium-241 86954-36-1 | Am 241.057 g/mol |  |
| Americium toxicity results primarily from the damage done by the alpha particle emitted during radioactive decay. This alpha particle has very limited penetration in t...more Number of Targets: 1 |
| T3D1328 | Lead hydroxide 19781-14-3 | H2O2Pb 241.200 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D1098 | Barium calcium titanium oxide 52869-93-9 | BaCaOTi 241.271 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D0983 | Methiocarb sulfoxide 2635-10-1 | C11H15NO3S 241.307 g/mol |  |
| Methiocarb sulfoxide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the ac...more Number of Targets: 2 |
| T3D3906 | Prometryn 7287-19-6 | C10H19N5S 241.356 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D4523 | Picloram 1918-02-1 | C6H3Cl3N2O2 241.459 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1775 | 1-Bromo-3-chloro-5,5-dimethylhydantoin 16079-88-2 | C5H6BrClN2O2 241.470 g/mol |  |
| BCDMH likely causes tissue irritation through its breakdown products (hypochlorous acid and hypobromous acid) which, on their own, can cause local irritation. 5,5-dim...more Number of Targets: 3 |
| T3D1228 | Copper lactate 814-81-3 | C6H10CuO6 241.686 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D3563 | Iron(III) nitrate 10421-48-4 | FeN3O9 241.860 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D1373 | Zinc cadmium sulfide 68583-45-9 | CdS2Zn 241.950 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 20 |
| T3D3918 | Quinclorac 84087-01-4 | C10H5Cl2NO2 242.058 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1546 | Aluminum sodium sulfate 10102-71-3 | AlNaO8S2 242.097 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D3962 | Equol 531-95-3 | C15H14O3 242.270 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2835 | Thiopental 76-75-5 | C11H18N2O2S 242.338 g/mol |  |
| Thiopental binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. T...more Number of Targets: 12 |
| T3D0237 | Ethoprop 13194-48-4 | C8H19O2PS2 242.339 g/mol |  |
| Ethoprop is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 8 |
| T3D4863 | 1-Hexadecanol 36653-82-4 | C16H34O 242.441 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1873 | Lithium hexafluoroantimonate(V) 18424-17-4 | F6LiSb 242.690 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D4784 | Clofibrate 637-07-0 | C12H15ClO3 242.699 g/mol |  |
| Clofibrate increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. Chylomicrons are degraded, VLDLs are ...more Number of Targets: 2 |
| T3D0178 | Americium 7440-35-9 | Am 243.000 g/mol |  |
| Americium toxicity results primarily from the damage done by the alpha particle emitted during radioactive decay. This alpha particle has very limited penetration in t...more Number of Targets: 1 |
| T3D4978 | Cytarabine 147-94-4 | C9H13N3O5 243.217 g/mol |  |
| Cytarabine acts through direct DNA damage and incorporation into DNA. Cytarabine is cytotoxic to a wide variety of proliferating mammalian cells in culture. It exhibit...more Number of Targets: 3 |
| T3D1470 | Zinc ammonium chloride 14639-97-5 | Cl4H8N2Zn 243.298 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D2954 | Frovatriptan 158747-02-5 | C14H17N3O 243.304 g/mol |  |
| Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT1D receptors, which serves t...more Number of Targets: 2 |