Browsing Toxins By Category
Displaying toxin 1551 - 1575 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4897 | Benzyl cinnamate 103-41-3 | C16H14O2 238.281 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2784 | Secobarbital 76-73-3 | C12H18N2O3 238.283 g/mol |  |
| Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open....more Number of Targets: 11 |
| T3D0995 | Pirimicarb 23103-98-2 | C11H18N4O2 238.286 g/mol |  |
| Pirimicarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 8 |
| T3D3692 | Agroclavine 548-42-5 | C16H18N2 238.328 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 6 |
| T3D4538 | TCMTB 21564-17-0 | C9H6N2S3 238.352 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 32 |
| T3D1343 | Mercury(II) fluoride 7783-39-3 | F2Hg 238.590 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D0316 | Sodium arsanilate 127-85-5 | C6H7AsNNaO3 239.036 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0121 | Plutonium-239 15117-48-3 | Pu 239.052 g/mol |  |
| The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more Number of Targets: 1 |
| T3D0331 | Lead dioxide 1309-60-0 | O2Pb 239.200 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D0336 | Lead sulfide 1314-87-0 | PbS 239.300 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D4735 | Salbutamol 18559-94-9 | C13H21NO3 239.311 g/mol |  |
| Salbutamol is a beta(2)-adrenergic agonist and thus it stimulates beta(2)-adrenergic receptors. Binding of albuterol to beta(2)-receptors in the lungs results in relax...more Number of Targets: 2 |
| T3D2919 | Benzphetamine 156-08-1 | C17H21N 239.355 g/mol |  |
| Although the mechanism of action of the sympathomimetic appetite suppressants in the treatment of obesity is not fully known, these medications have pharmacological ef...more Number of Targets: 5 |
| T3D4487 | Clomazone 81777-89-1 | C12H14ClNO2 239.698 g/mol |  |
| Clomazone induces oxidative stress and AChE inhibition in human erythrocytes (in vitro), suggesting a role for reactive oxygen species in the toxicity mechanism induce...more Number of Targets: 8 |
| T3D2999 | Bupropion 34841-39-9 | C13H18ClNO 239.741 g/mol |  |
| Bupropion selectively inhibits the neuronal reuptake of dopamine, norepinephrine, and serotonin; actions on dopaminergic systems are more significant than imipramine o...more Number of Targets: 14 |
| T3D0387 | Cadmium telluride 1306-25-8 | CdTe 240.000 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 19 |
| T3D0140 | Plutonium-240 14119-33-6 | Pu 240.054 g/mol |  |
| The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more Number of Targets: 1 |
| T3D1238 | Monomethyltin trichloride 993-16-8 | CH3Cl3Sn 240.100 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D0698 | Nickel subsulfide 12035-72-2 | Ni3S2 240.210 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D4873 | (±)-2-(1-Methylpropyl)-4,6-dinitrophenol 88-85-7 | C10H12N2O5 240.213 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D1111 | Barium hypochlorite 13477-10-6 | BaCl2O2 240.232 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D4197 | 3-Carboxy-4-methyl-5-propyl-2-furan-propanoic acid 86879-39-2 | C12H16O5 240.252 g/mol |  |
| Uremic toxins such as 3-Carboxy-4-methyl-5-propyl-2-furan-propanoic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Incr...more Number of Targets: 3 |
| T3D0961 | Dimetilan 644-64-4 | C10H16N4O3 240.259 g/mol |  |
| Dimetilan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D4479 | Bentazon 25057-89-0 | C10H12N2O3S 240.279 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3696 | Costaclavine 436-41-9 | C16H20N2 240.343 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 4 |
| T3D4542 | Thiram 137-26-8 | C6H12N2S4 240.433 g/mol |  |
| Not Available Number of Targets: 33 |