Browsing Toxins By Category
Displaying toxin 1501 - 1525 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1608 | Silver iodide 7783-96-2 | AgI 234.773 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D1246 | Dibutyltin hydride 1002-53-5 | C8H20Sn 234.950 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1261 | Tetraethyltin 597-64-8 | C8H20Sn 234.950 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D0108 | Uranium-235 15117-96-1 | U 235.044 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D0801 | Dichlorprop 120-36-5 | C9H8Cl2O3 235.064 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 6 |
| T3D2665 | Pamidronate 40391-99-9 | C3H11NO7P2 235.070 g/mol |  |
| The mechanism of action of pamidronate is inhibition of bone resorption. Pamidronate adsorbs to calcium phosphate (hydroxyapatite) crystals in bone and may directly bl...more Number of Targets: 3 |
| T3D0905 | 3-Oxo-carbofuran 16709-30-1 | C12H13NO4 235.236 g/mol |  |
| 3-Oxo-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active...more Number of Targets: 2 |
| T3D4483 | Carboxin 5234-68-4 | C12H13NO2S 235.302 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D0901 | 3,5-Diisopropylphenyl methylcarbamate 330-64-3 | C14H21NO2 235.322 g/mol |  |
| 3,5-Diisopropylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamo...more Number of Targets: 2 |
| T3D1717 | Silver bromate 7783-89-3 | AgBrO3 235.770 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 23 |
| T3D0654 | Cobalt(III) acetate 917-69-1 | C6H9CoO6 236.065 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D4786 | Didanosine 69655-05-6 | C10H12N4O3 236.227 g/mol |  |
| Didanosine (ddI) is metabolized intracellularly by a series of cellular enzymes to its active moiety, dideoxyadenosine triphosphate (ddATP), which inhibits the HIV rev...more Number of Targets: 2 |
| T3D0194 | Bis(2-methoxyethyl) phthalate 34006-76-3 | C13H16O4 236.264 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D3039 | Hexobarbital 56-29-1 | C12H16N2O3 236.267 g/mol |  |
| Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A receptor, increasing the duration of time for which the Cl- ionopore is open...more Number of Targets: 11 |
| T3D0912 | 4-Methylformamido-3,5-xylyl methylcarbamate 10233-94-0 | C12H16N2O3 236.267 g/mol |  |
| 4-Methylformamido-3,5-xylyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by c...more Number of Targets: 2 |
| T3D0943 | Carbetamide 16118-49-3 | C12H16N2O3 236.267 g/mol |  |
| Carbetamide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D2826 | Carbamazepine 298-46-4 | C15H12N2O 236.269 g/mol |  |
| Carbamazepine inhibits sustained repetitive firing by blocking use-dependent sodium channels. Pain relief is believed to be associated with blockade of synaptic transm...more Number of Targets: 14 |
| T3D1051 | (2E)-3-Benzyl-2-(nitromethylidene)-1,3-thiazolidine 94776-91-7 | C11H12N2O2S 236.290 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D4887 | Heptyl 4-hydroxybenzoate 1085-12-7 | C14H20O3 236.307 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D2869 | Procaine 59-46-1 | C13H20N2O2 236.310 g/mol |  |
| Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is...more Number of Targets: 11 |
| T3D0044 | 1,2-Dibromo-3-chloropropane 96-12-8 | C3H5Br2Cl 236.333 g/mol |  |
| The initial metabolism of 1,2-dibromo-3-chloropropane to reactive epoxide metabolites that bind to DNA and other macromolecules may be responsible for its hepatotoxici...more Number of Targets: 54 |
| T3D0378 | Cadmium nitrate 10325-94-7 | CdN2O6 236.421 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 28 |
| T3D1872 | Hexafluoroantimonic acid 16950-06-4 | F6HSb 236.760 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D0136 | Neptunium-237 13994-20-2 | Np 237.048 g/mol |  |
| The ionizing radiation produced by neptunium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal c...more Number of Targets: 1 |
| T3D2191 | 1,2-Dichlorodibenzofuran 64126-85-8 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |