Browsing Toxins By Category
Displaying toxin 1476 - 1500 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0341 | Mercury(II) sulfide 1344-48-5 | HgS 232.660 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D0179 | Uranium-233 13968-55-3 | U 233.040 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D4500 | Diuron 330-54-1 | C9H10Cl2N2O 233.095 g/mol |  |
| Diuron has been reported to bind to androgen receptors. This suggests that diuron may block the receptors and result in the toxicity on the reproductive system. Number of Targets: 8 |
| T3D1917 | 2-Monobromobiphenyl 252-07-7 | C12H9Br 233.104 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1944 | 3-Monobromobiphenyl 2113-57-7 | C12H9Br 233.104 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2018 | 4-Monobromobiphenyl 92-66-0 | C12H9Br 233.104 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1124 | Barium titanate 12047-27-7 | BaO3Ti 233.192 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D4563 | Dexmethylphenidate 40431-64-9 | C14H19NO2 233.306 g/mol |  |
| Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal...more Number of Targets: 3 |
| T3D2786 | Methylphenidate 113-45-1 | C14H19NO2 233.306 g/mol |  |
| Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal...more Number of Targets: 3 |
| T3D1122 | Barium sulfate 7727-43-7 | BaO4S 233.390 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D4700 | Lomustine 13010-47-4 | C9H16ClN3O2 233.695 g/mol |  |
| Lomustine is a highly lipophilic nitrosourea compound which undergoes hydrolysis in vivo to form reactive metabolites. These metabolites cause alkylation and cross-lin...more Number of Targets: 2 |
| T3D0111 | Uranium-234 13966-29-5 | U 234.041 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D0894 | 2,3-Dichlorobenzyl methylcarbamate 62046-37-1 | C9H9Cl2NO2 234.079 g/mol |  |
| 2,3-Dichlorobenzyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoyla...more Number of Targets: 2 |
| T3D0900 | 3,4-Dichlorobenzyl methylcarbamate 2328-31-6 | C9H9Cl2NO2 234.079 g/mol |  |
| 3,4-Dichlorobenzyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoyla...more Number of Targets: 2 |
| T3D0957 | Dichlormate 1966-58-1 | C9H9Cl2NO2 234.079 g/mol |  |
| Dichlormate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D2875 | Riluzole 1744-22-5 | C8H5F3N2OS 234.198 g/mol |  |
| The mode of action of riluzole is unknown. Its pharmacological properties include the following, some of which may be related to its effect: 1) an inhibitory effect on...more Number of Targets: 5 |
| T3D1076 | Methyl (5Z)-3-amino-5-(nitromethylidene)dithiole-4-carboxylate 78649-93-1 | C6H6N2O4S2 234.253 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D4994 | Dibenzylideneacetone 538-58-9 | C17H14O 234.293 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D0975 | Hyquincarb 56716-21-3 | C13H18N2O2 234.294 g/mol |  |
| Hyquincarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 2 |
| T3D3713 | Scirpene 37133-74-7 | C15H22O2 234.334 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D2735 | Lidocaine 137-58-6 | C14H22N2O 234.337 g/mol |  |
| Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic act...more Number of Targets: 10 |
| T3D0895 | 2,4-Dimethyl-1,3-dithiolane-2-carboxaldehyde O-(methylcarbamoyl)oxime 26419-73-8 | C8H14N2O2S2 234.339 g/mol |  |
| 2,4-Dimethyl-1,3-dithiolane-2-carboxaldehyde O-(methylcarbamoyl)oxime is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes ...more Number of Targets: 2 |
| T3D4922 | 2,6-Di-tert-butyl-4-ethylphenol 4130-42-1 | C16H26O 234.377 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1588 | trans-Diamminedinitro-palladium(II) 28068-05-5 | H8N4O4Pd 234.510 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1615 | Silver subfluoride 1302-01-8 | Ag2F 234.735 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |