Browsing Toxins By Category
Displaying toxin 1451 - 1475 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0896 | 2-Chloro-4,5-xylyl N-hydroxy-N-methylcarbamate 14357-82-5 | C10H12ClNO3 229.660 g/mol |  |
| 2-Chloro-4,5-xylyl N-hydroxy-N-methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases b...more Number of Targets: 2 |
| T3D3908 | Propazine 139-40-2 | C9H16ClN5 229.710 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D0292 | Arsenic pentoxide 1303-28-2 | As2O5 229.840 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0107 | Thorium-230 14269-63-7 | Th 230.033 g/mol |  |
| The ionizing radiation produced by thorium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal cha...more Number of Targets: 1 |
| T3D2829 | Clonidine 4205-90-7 | C9H9Cl2N3 230.094 g/mol |  |
| Clonidine acts as an agonist at presynaptic alpha(2)-receptors in the nucleus tractus solitarius of the medulla oblongata. Stimulation of these receptors results in th...more Number of Targets: 7 |
| T3D0923 | Asulam 3337-71-1 | C8H10N2O4S 230.241 g/mol |  |
| Asulam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesterase...more Number of Targets: 6 |
| T3D1577 | Palladium(II) nitrate 10102-05-3 | N2O6Pd 230.430 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 15 |
| T3D0364 | Cadmium acetate 543-90-8 | C4H6CdO4 230.499 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 19 |
| T3D0361 | Dimethyl mercury 593-74-8 | C2H6Hg 230.660 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D1134 | Manganese(III) oxide 1317-35-7 | H2Mn3O4 230.828 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D3892 | Nitrapyrin 1929-82-4 | C6H3Cl4N 230.907 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D3033 | Isocarboxazid 59-63-2 | C12H13N3O2 231.251 g/mol |  |
| Isocarboxazid works by irreversibly blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system. MAO subtypes A and B are involv...more Number of Targets: 2 |
| T3D3014 | Dexfenfluramine 3239-44-9 | C12H16F3N 231.257 g/mol |  |
| Dexfenfluramine binds to the serotonin reuptake pump. This causes inhbition of serotonin reuptake. The increased levels of serotonin lead to greater serotonin receptor...more Number of Targets: 4 |
| T3D1009 | Tazimcarb 40085-57-2 | C8H13N3O3S 231.272 g/mol |  |
| Tazimcarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D0734 | Zinc molybdate 13767-32-3 | H6MoO4Zn 231.390 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1612 | Silver oxide 20667-12-3 | Ag2O 231.736 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D0870 | 2,3,5,6-Tetrachlorophenol 935-95-5 | C6H2Cl4O 231.891 g/mol |  |
| 2,3,5,6-tetrachlorophenol acts at the sites of adenosine triphosphate production and decreases or blocks it without blocking the electron transport chain. Thus the poi...more Number of Targets: 2 |
| T3D0177 | 2,3,4,5-Tetrachlorophenol 25167-83-3 | C6H2Cl4O 231.891 g/mol |  |
| Tetrachlorophenols decrease or block ATP production without blocking the electron transport chain. Thus the poisons uncouple phosphorylation from oxidation. Free energ...more Number of Targets: 2 |
| T3D0101 | Thorium 7440-29-1 | Th 232.038 g/mol |  |
| The ionizing radiation produced by thorium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal cha...more Number of Targets: 1 |
| T3D0845 | 9-Hydroxy-4-methoxypsoralen 1603-47-0 | C12H8O5 232.189 g/mol |  |
| The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more Number of Targets: 3 |
| T3D4511 | Fluometuron 2164-17-2 | C10H11F3N2O 232.202 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3006 | Phenobarbital 50-06-6 | C12H12N2O3 232.235 g/mol |  |
| Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. This has the effect of elevating seizure threshold and reducing the spread of seizure activity f...more Number of Targets: 9 |
| T3D2972 | Melatonin 73-31-4 | C13H16N2O2 232.278 g/mol |  |
| Melatonin is a derivative of tryptophan. It binds to melatonin receptor type 1A, which then acts on adenylate cylcase and the inhibition of a cAMP signal transduction ...more Number of Targets: 18 |
| T3D4806 | Aminoglutethimide 125-84-8 | C13H16N2O2 232.278 g/mol |  |
| Aminoglutethimide reduces the production of D5-pregnenolone and blocks several other steps in steroid synthesis, including the C-11, C-18, and C-21 hydroxylations and ...more Number of Targets: 2 |
| T3D0724 | Zinc chlorate 10361-95-2 | Cl2O6Zn 232.311 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |