Browsing Toxins By Category
Displaying toxin 1401 - 1425 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0962 | Dioxacarb 6988-21-2 | C11H13NO4 223.225 g/mol |  |
| Dioxacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D2964 | Cerulenin 17397-89-6 | C12H17NO3 223.268 g/mol |  |
| Irreversibly binds to fatty acid synthase, specifically b-ketoacyl-acyl carrier protein synthase (FabH, FabB and FabF condensation enzymes). A number of tumor cells an...more Number of Targets: 1 |
| T3D0915 | 6-Methyl-2-propyl-4-pyrimidinyl dimethylcarbamate 2532-49-2 | C11H17N3O2 223.272 g/mol |  |
| 6-Methyl-2-propyl-4-pyrimidinyl dimethylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterase...more Number of Targets: 2 |
| T3D1207 | Copper(II) bromide 7789-45-9 | Br2Cu 223.354 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 12 |
| T3D0719 | Zinc chromate hydroxide 15930-94-6 | CrH10O6Zn 223.481 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 6 |
| T3D0947 | Chlorbufam 1967-16-4 | C11H10ClNO2 223.656 g/mol |  |
| Chlorbufam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 1 |
| T3D1006 | Sulfallate 95-06-7 | C8H14ClNS2 223.786 g/mol |  |
| The metabolic products of triallate, diallate and sulfallate appear to be mutagenic or carcinogenic. In particular, the 2-chloro-allyl group is responsible for the mu...more Number of Targets: 3 |
| T3D3884 | Mevinphos 7786-34-7 | C7H13O6P 224.148 g/mol |  |
| Mevinphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 10 |
| T3D4772 | Stavudine 3056-17-5 | C10H12N2O4 224.213 g/mol |  |
| Stavudine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA. Number of Targets: 1 |
| T3D4581 | 1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine 105650-23-5 | C13H12N4 224.261 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1575 | Palladium(II) acetate 3375-31-3 | C4H6O4Pd 224.510 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1000 | Propamocarb hydrochloride 25606-41-1 | C9H21ClN2O2 224.728 g/mol |  |
| Propamocarb hydrochloride is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of t...more Number of Targets: 5 |
| T3D0330 | Lead oxide 1317-36-8 | H2OPb 225.200 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D0723 | Zinc bromide 7699-45-8 | Br2Zn 225.217 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 7 |
| T3D3820 | Cyprodinil 121552-61-2 | C14H15N3 225.289 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D3905 | Prometon 1610-18-0 | C10H19N5O 225.291 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D0964 | Ethiofencarb 29973-13-5 | C11H15NO2S 225.307 g/mol |  |
| Ethiofencarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 |
| T3D0981 | Methiocarb 2032-65-7 | C11H15NO2S 225.307 g/mol |  |
| Methiocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 2 |
| T3D1116 | Barium oxalate 516-02-9 | C2BaO4 225.346 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D1306 | Cacodyl oxide 503-80-0 | C4H12As2O 225.981 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0100 | Radium-226 13982-63-3 | Ra 226.025 g/mol |  |
| Ionizing radiation produced by radium damages the DNA, resulting in gene mutations and chromosomal aberrations. This can both initiate and promote carcinogenesis, and ...more Number of Targets: 1 |
| T3D4274 | Porphobilinogen 487-90-1 | C10H14N2O4 226.229 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4561 | Amobarbital 57-43-2 | C11H18N2O3 226.272 g/mol |  |
| Amobarbital (like all barbiturates) works by binding to the GABAA receptor at either the alpha or the beta sub unit. These are binding sites that are distinct from GA...more Number of Targets: 10 |
| T3D2745 | Pentobarbital 76-74-4 | C11H18N2O3 226.272 g/mol |  |
| Pentobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open...more Number of Targets: 16 |
| T3D1464 | Zinc silicate 13597-65-4 | H4O4SiZn2 226.933 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |