Browsing Toxins By Category
Displaying toxin 1326 - 1350 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0342 | Mercury(II) oxide 21908-53-2 | HgO 216.590 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D4539 | Terbacil 5902-51-2 | C9H13ClN2O2 216.665 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0300 | Arsanilic acid 98-50-0 | C6H8AsNO3 217.054 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 |
| T3D3913 | Pymetrozine 123312-89-0 | C10H11N5O 217.227 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4874 | Ethoxyquin 91-53-2 | C14H19NO 217.307 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D4481 | Butylate 2008-41-5 | C11H23NOS 217.371 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D1138 | Methylcyclopentadienyl manganese tricarbonyl 12108-13-3 | C9H7MnO3 218.088 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D1060 | (2Z)-1-Benzyl-2-(nitromethylidene)pyrrolidine 57734-58-4 | C12H14N2O2 218.252 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1014 | Thiofanox 39196-18-4 | C9H18N2O2S 218.316 g/mol |  |
| Thiofanox is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D0691 | Nickel bromide 13462-88-9 | Br2Ni 218.501 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 74 |
| T3D2046 | 1-Chlorodibenzo-p-dioxin 39227-53-7 | C12H7ClO2 218.636 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2047 | 2-Chlorodibenzo-p-dioxin 39227-54-8 | C12H7ClO2 218.636 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2331 | 8-Chloro-3-dibenzofuranol 51596-39-5 | C12H7ClO2 218.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D3814 | Clorophene 120-32-1 | C13H11ClO 218.679 g/mol |  |
| AR binding was observed for clorophene, which were both associated with delays in sexual development and decrements in reproductive performance. Number of Targets: 17 |
| T3D0658 | Cobalt(II) bromide 7789-43-7 | Br2Co 218.741 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 42 |
| T3D1385 | Cobalt(II) molybdenum(VI) oxide 13762-14-6 | CoMoO4 218.870 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1625 | Vanadium carbonyl 20644-87-5 | C6O6V 219.002 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D0992 | Oxamyl 23135-22-0 | C7H13N3O3S 219.261 g/mol |  |
| Oxamyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of ...more Number of Targets: 5 |
| T3D0897 | 2-Cyclopentylphenyl methylcarbamate 3282-00-6 | C13H17NO2 219.280 g/mol |  |
| 2-Cyclopentylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoyl...more Number of Targets: 2 |
| T3D1015 | Tillam sulfoxide 51892-60-5 | C10H21NO2S 219.344 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 2 |
| T3D1239 | Dimethyltin dichloride 753-73-1 | C2H6Cl2Sn 219.690 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D0130 | Radon-220 22481-48-7 | Rn 220.011 g/mol |  |
| The ionizing radiation produced by radon causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal chang...more Number of Targets: 1 |
| T3D1008 | Swep 1918-18-9 | C8H7Cl2NO2 220.053 g/mol |  |
| Swep is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of th...more Number of Targets: 2 |
| T3D1431 | Chromium carbonyl 13007-92-6 | C6CrO6 220.057 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D4298 | 5-Hydroxy-L-tryptophan 4350-09-8 | C11H12N2O3 220.225 g/mol |  |
| 5-Hydroxy-L-tryptophan is the immediate precursor of the neurotransmitter serotonin. An accumulation of 5-hydroxy-L-tryptophan in cerebrospinal fluid occurs in aromati...more Number of Targets: 1 |