Browsing Toxins By Category
Displaying toxin 1276 - 1300 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2577 | Varenicline 249296-44-4 | C13H13N3 211.262 g/mol |  |
| Varenicline is an alpha-4 beta-2 neuronal nicotinic acetylcholine receptor partial agonist. The drug shows high selectiviyty for this receptor subclass, relative to ot...more Number of Targets: 4 |
| T3D0908 | 4-(Methylthio)-m-tolyl methylcarbamate 3566-00-5 | C10H13NO2S 211.281 g/mol |  |
| 4-(Methylthio)-m-tolyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbam...more Number of Targets: 2 |
| T3D0911 | 4-Ethylthiophenyl methylcarbamate 18809-57-9 | C10H13NO2S 211.281 g/mol |  |
| 4-Ethylthiophenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylat...more Number of Targets: 2 |
| T3D1007 | Sulfocarbathione 114654-31-8 | C5H9NO2S3 211.325 g/mol |  |
| Sulfocarbathione is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active...more Number of Targets: 2 |
| T3D2783 | Pramipexole 104632-26-0 | C10H17N3S 211.327 g/mol |  |
| The precise mechanism of action of Pramipexole as a treatment for Parkinson's disease is unknown, although it is believed to be related to its ability to stimulate dop...more Number of Targets: 14 |
| T3D1585 | cis-Diamminedichloro-palladium(II) 14323-43-4 | Cl2H6N2Pd 211.390 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1477 | Zinc propionate 557-28-8 | C6H10O4Zn 211.550 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1227 | Copper tartrate 27004-40-6 | C4H4CuO6 211.617 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D3575 | Strontium nitrate 10042-76-9 | N2O6Sr 211.630 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D1090 | Propachlor 1918-16-7 | C11H14ClNO 211.688 g/mol |  |
| Propachlor poisoning causes an induction of microsomal hepatic UDPGT activity, which produces increased clearance of thyroid hormone, T4. Decreased levels of T4 would ...more Number of Targets: 17 |
| T3D1725 | Bronidox 30007-47-7 | C4H6BrNO4 211.999 g/mol |  |
| Bronidox likely acts as an oxidizing agent that leads to oxidation of free sulfhydryls in essential enzymes. One of the most probable protein targets is the TRPA1 ion...more Number of Targets: 1 |
| T3D4850 | Propyl gallate 121-79-9 | C10H12O5 212.199 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D2928 | Zonisamide 68291-97-4 | C8H8N2O3S 212.226 g/mol |  |
| Zonisamide binds to sodium channels and voltage sensitive calcium channels, which suppresses neuronal depolarization and hypersynchronization. Zonisamide also inhibits...more Number of Targets: 31 |
| T3D4906 | Benzoin 119-53-9 | C14H12O2 212.244 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3038 | Butethal 77-28-1 | C10H16N2O3 212.246 g/mol |  |
| Butethal binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The...more Number of Targets: 10 |
| T3D2721 | Butabarbital 125-40-6 | C10H16N2O3 212.246 g/mol |  |
| Butabarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open....more Number of Targets: 6 |
| T3D4782 | Pentadecane 629-62-9 | C15H32 212.415 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1726 | Cesium bromide 7787-69-1 | BrCs 212.809 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1141 | Manganese diselenide 12299-98-8 | MnSe2 212.860 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D1515 | Aluminium nitrate 13473-90-0 | AlN3O9 212.996 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 12 |
| T3D0103 | 1,3,5-Trinitrobenzene 99-35-4 | C6H3N3O6 213.105 g/mol |  |
| In the red blood cell, 1,3,5-TNB induces formation of methemoglobin, leading to cyanosis. Reduction of the nitrogroup(s) of 1,3,5-TNB produces reactive nitroaromatic r...more Number of Targets: 0 |
| T3D4158 | Indoxyl sulfate 487-94-5 | C8H7NO4S 213.210 g/mol |  |
| Uremic toxins such as Indoxyl sulfate are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can s...more Number of Targets: 6 |
| T3D4810 | N-Butyl-Benzenesulfonamide 3622-84-2 | C10H15NO2S 213.297 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1225 | Copper chloride hydroxide 1332-65-6 | ClCu2H3O3 213.567 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D2554 | Baclofen 1134-47-0 | C10H12ClNO2 213.661 g/mol |  |
| Baclofen is a direct agonist at GABAB receptors. The precise mechanism of action of Baclofen is not fully known. It is capable of inhibiting both monosynaptic and poly...more Number of Targets: 3 |