Browsing Toxins By Category
Displaying toxin 1251 - 1275 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0922 | Aminocarb 2032-59-9 | C11H16N2O2 208.257 g/mol |  |
| Aminocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D2979 | Pilocarpine 54-71-7 | C11H16N2O2 208.257 g/mol |  |
| Pilocarpine is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary...more Number of Targets: 4 |
| T3D0249 | Dibromochloromethane 124-48-1 | CHBr2Cl 208.280 g/mol |  |
| Dibromochloromethane is oxidized into trihalomethanol by the cytochrome P-450 mixed function oxidase system of liver. Trihalomethanol then decomposes by loss of hydrog...more Number of Targets: 2 |
| T3D0384 | Cadmium sulfate 10124-36-4 | CdO4S 208.474 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 19 |
| T3D2530 | Epibatidine 140111-52-0 | C11H13ClN2 208.687 g/mol |  |
| Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074) Number of Targets: 17 |
| T3D1067 | 3-[(2E)-2-(Nitromethylidene)hydrazinyl]benzoic acid 91978-88-0 | C8H7N3O4 209.159 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1003 | Propoxur 114-26-1 | C11H15NO3 209.242 g/mol |  |
| Propoxur is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 13 |
| T3D3984 | 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol 76014-81-8 | C10H15N3O2 209.245 g/mol |  |
| 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is a substrate of UDP-glucuronyl transferase, leading to the formation of [4-(methylnitrosamino)-1-(3-pyridyl)but-...more Number of Targets: 0 |
| T3D1706 | Octyl cyanoacrylate 6701-17-3 | C12H19NO2 209.285 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1586 | trans-Diamminedichloro-palladium(II) 13782-33-7 | Cl2H4N2Pd 209.370 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1533 | Sodium hexafluoroaluminate 13775-53-6 | AlF6Na3 209.941 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1305 | Cacodyl 471-35-2 | C4H12As2 209.981 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0122 | Polonium-210 13981-52-7 | Po 209.983 g/mol |  |
| The alpha radiation polonium emits does not penetrate the skin but can irradiate internal organs when polonium is inhaled or ingested. The ionizing radiation produced ...more Number of Targets: 1 |
| T3D0125 | Lead-210 14255-04-0 | Pb 209.984 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 30 |
| T3D3523 | Methyl ethyl ketone peroxide 1338-23-4 | C8H18O6 210.225 g/mol |  |
| MEPK toxicity could occur through lipid peroxidation. (L1789) Number of Targets: 0 |
| T3D1066 | (3Z)-2-Ethyl-3-(nitromethylidene)-3a,4,5,6,7,7a-hexahydro-1H-isoindole 56593-86-3 | C11H18N2O2 210.273 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D3789 | Acibenzolar-S-Methyl 135158-54-2 | C8H6N2OS2 210.276 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4885 | 2-Ethyl-1-hexanol sulfate 126-92-1 | C8H18O4S 210.291 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4918 | Isobornyl propionate 2756-56-1 | C13H22O2 210.313 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1329 | Plumbane 15875-18-0 | H4Pb 211.200 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D3577 | Methyldopa 555-30-6 | C10H13NO4 211.215 g/mol |  |
| Although the mechanism of action has yet to be conclusively demonstrated, the resultant hypotensive effect is most likely due to the drug's action on the CNS. Methyldo...more Number of Targets: 4 |
| T3D4719 | Zalcitabine 7481-89-2 | C9H13N3O3 211.218 g/mol |  |
| Zalcitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Within cells, zalcitabine is conv...more Number of Targets: 0 |
| T3D4979 | Isoprenaline 7683-59-2 | C11H17NO3 211.258 g/mol |  |
| The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzy...more Number of Targets: 7 |
| T3D0960 | Dimetan 122-15-6 | C11H17NO3 211.258 g/mol |  |
| Dimetan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of...more Number of Targets: 2 |
| T3D0976 | Isolan 119-38-0 | C10H17N3O2 211.261 g/mol |  |
| Isolan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of ...more Number of Targets: 2 |