Browsing Toxins By Category
Displaying toxin 1201 - 1225 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4176 | Symmetric dimethylarginine 30344-00-4 | C8H18N4O2 202.254 g/mol |  |
| Uremic toxins such as symmetric dimethylarginine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic t...more Number of Targets: 3 |
| T3D4908 | 2-Pentyl-3-phenyl-2-propenal 122-40-7 | C14H18O 202.292 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4166 | Spermine 71-44-3 | C10H26N4 202.340 g/mol |  |
| Uremic toxins such as spermine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulat...more Number of Targets: 21 |
| T3D1592 | Palladium(II) sulfate 566-03-5 | O4PdS 202.480 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D2215 | 1-Chlorodibenzofuran 42934-53-2 | C12H7ClO 202.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2268 | 2-Chlorodibenzofuran 51230-49-0 | C12H7ClO 202.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2286 | 3-Chlorodibenzofuran 25074-67-3 | C12H7ClO 202.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2307 | 4-Chlorodibenzofuran 74992-96-4 | C12H7ClO 202.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D3069 | Methsuximide 77-41-8 | C12H13NO2 203.237 g/mol |  |
| Methsuximide suppresses the paroxysmal three cycle per second spike and wave activity associated with lapses of consciousness which is common in absence (petit mal) se...more Number of Targets: 1 |
| T3D0993 | Pebulate 1114-71-2 | C10H21NOS 203.345 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 4 |
| T3D1020 | Vernolate 1929-77-7 | C10H21NOS 203.345 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 4 |
| T3D0712 | Strontium chromate 7789-06-2 | CrO4Sr 203.610 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D1488 | Aluminum triacetate 139-12-8 | C6H9AlO6 204.114 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1711 | Tetracyanoquinodimethane 1518-16-7 | C12H4N4 204.187 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4198 | N(6)-Carboxymethyllysine 5746-04-3 | C8H16N2O4 204.224 g/mol |  |
| Uremic toxins such as carboxymethyllysine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins c...more Number of Targets: 3 |
| T3D1054 | (4E)-4-(Nitromethylidene)-1,2,3,5-tetrahydro-3-benzazepine 58350-08-6 | C11H12N2O2 204.225 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D2883 | Ethotoin 86-35-1 | C11H12N2O2 204.225 g/mol |  |
| The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to p...more Number of Targets: 2 |
| T3D4369 | L-Tryptophan 73-22-3 | C11H12N2O2 204.225 g/mol |  |
| A number of important side reactions occur during the catabolism of tryptophan on the pathway to acetoacetate. The first enzyme of the catabolic pathway is an iron por...more Number of Targets: 7 |
| T3D1510 | Aluminium isopropoxide 555-31-7 | C9H21AlO3 204.243 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D2458 | Psilocin 520-53-6 | C12H16N2O 204.268 g/mol |  |
| Psilocin acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). It is an 5-HT1A and 5-HT2A/2C agonist...more Number of Targets: 3 |
| T3D2534 | Bufotenin 487-93-4 | C12H16N2O 204.268 g/mol |  |
| Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. Thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimic...more Number of Targets: 4 |
| T3D4878 | 2,4-Di-tert-butylphenol 96-76-4 | C14H20O 204.308 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D3975 | Thallium 7440-28-0 | Tl 204.383 g/mol |  |
| Thallium(I) compounds have a high aqueous solubility and are readily absorbed through the skin. Part of the reason for thallium's high toxicity is that, when present i...more Number of Targets: 22 |
| T3D1697 | Carbonyl cyanide m-chlorophenyl hydrazone 555-60-2 | C9H5ClN4 204.616 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D0990 | o-(2-Propynyloxy)phenyl methylcarbamate 3279-46-7 | C11H11NO3 205.210 g/mol |  |
| o-(2-Propynyloxy)phenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carba...more Number of Targets: 2 |