Browsing Toxins By Category
Displaying toxin 1176 - 1200 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1240 | Trimethyltin chloride 1066-45-1 | C3H9ClSn 199.270 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1727 | Calcium bromide 7789-41-5 | Br2Ca 199.886 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1724 | Bronopol 52-51-7 | C3H6BrNO4 199.988 g/mol |  |
| While Bronopol is not in itself a nitrosating agent, under conditions where it decomposes (alkaline solution and/or elevated temperatures) it can liberate nitrite and ...more Number of Targets: 9 |
| T3D3029 | Sevoflurane 28523-86-6 | C4H3F7O 200.055 g/mol |  |
| Sevoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Sevoflura...more Number of Targets: 8 |
| T3D1448 | Chromium(III) sulfide 12018-22-3 | Cr2S3 200.187 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D4434 | S-Sulfocysteine 1637-71-4 | C3H6NO5S2 200.214 g/mol |  |
| S-Sulfocysteine (SSC) is a very potent NMDA-receptor agonist. Electrophysiological studies have shown that SSC displays depolarizing properties similar to glutamate. S...more Number of Targets: 3 |
| T3D4596 | Dodecanoic acid 143-07-7 | C12H24O2 200.318 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D0003 | Mercury 7439-97-6 | Hg 200.590 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 53 |
| T3D0804 | 2-Methyl-4-chlorophenoxyacetic acid 94-74-6 | C9H9ClO3 200.619 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 6 |
| T3D3812 | Cloprop 101-10-0 | C9H9ClO3 200.619 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D1409 | Nickel arsenate 13477-70-8 | AsH3NiO4 200.636 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 112 |
| T3D0940 | Carbaril 63-25-2 | C12H11NO2 201.221 g/mol |  |
| Carbaril is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 15 |
| T3D1012 | Thiocarboxime 25171-63-5 | C7H11N3O2S 201.246 g/mol |  |
| Thiocarboxime is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active si...more Number of Targets: 2 |
| T3D3931 | Thiabendazole 148-79-8 | C10H7N3S 201.248 g/mol |  |
| The precise mode of action of thiabendazole on the parasite is unknown, but it most likely inhibits the helminth-specific enzyme fumarate reductase. Number of Targets: 17 |
| T3D3922 | Simazine 122-34-9 | C7H12ClN5 201.657 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D1796 | 1,2-Dibromopropane 78-75-1 | C3H6Br2 201.888 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D1797 | 1,3-Dibromopropane 109-64-8 | C3H6Br2 201.888 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D0310 | Benzenearsonic acid 98-05-5 | C6H7AsO3 202.040 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 52 |
| T3D1531 | Sodium bis(2-methoxyethoxy)aluminumhydride 22722-98-1 | C6H16AlNaO4 202.160 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4999 | Succinyl acetoacetate 65115-74-4 | C8H10O6 202.161 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D2454 | L-Coprine 58919-61-2 | C8H14N2O4 202.208 g/mol |  |
| It metabolises to 1-aminocyclopropanol, a closely-related chemical to Disulfiram and exhibits the same mechanism of action: inhibition of the enzyme acetaldehyde dehyd...more Number of Targets: 8 |
| T3D4883 | Sebacic acid 111-20-6 | C10H18O4 202.248 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0110 | Fluoranthene 206-44-0 | C16H10 202.251 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 6 |
| T3D0253 | Pyrene 129-00-0 | C16H10 202.251 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 8 |
| T3D4171 | Asymmetric dimethylarginine 30315-93-6 | C8H18N4O2 202.254 g/mol |  |
| Uremic toxins such as asymmetric dimethylarginine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic ...more Number of Targets: 5 |