Browsing Toxins By Category
Displaying toxin 1151 - 1175 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3028 | L-Dopa 59-92-7 | C9H11NO4 197.188 g/mol |  |
| Striatal dopamine levels in symptomatic Parkinson's disease are decreased by 60 to 80%, striatal dopaminergic neurotransmission may be enhanced by exogenous supplement...more Number of Targets: 8 |
| T3D4199 | Dihydroxyphenylalanine 63-84-3 | C9H11NO4 197.188 g/mol |  |
| Uremic toxins such as dihydroxyphenylalanine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxin...more Number of Targets: 3 |
| T3D0989 | Nitrilacarb 29672-19-3 | C9H15N3O2 197.234 g/mol |  |
| Nitrilacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D1099 | Barium carbonate 513-77-9 | CBaO3 197.336 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D1092 | Barium acetate 543-80-6 | C2H4BaO2 197.378 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D3001 | Halothane 151-67-7 | C2HBrClF3 197.382 g/mol |  |
| Halothane causes general anaethesia due to its actions on multiple ion channels, which ultimately depresses nerve conduction, breathing, cardiac contractility. Its imm...more Number of Targets: 22 |
| T3D0086 | 2,4,6-Trichlorophenol 88-06-2 | C6H3Cl3O 197.446 g/mol |  |
| 2,4,6-Trichlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more Number of Targets: 40 |
| T3D0222 | 2,4,5-Trichlorophenol 95-95-4 | C6H3Cl3O 197.446 g/mol |  |
| 2,4,5-Trichlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more Number of Targets: 6 |
| T3D1266 | Tin selenide 1315-06-0 | SeSn 197.670 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 7 |
| T3D0224 | Arsenic trioxide 1327-53-3 | As2O3 197.841 g/mol |  |
| The mechanism of action of Arsenic Trioxide is not completely understood. Arsenic trioxide causes morphological changes and DNA fragmentation characteristic of apoptos...more Number of Targets: 51 |
| T3D0102 | 4,6-Dinitro-o-cresol 534-52-1 | C7H6N2O5 198.133 g/mol |  |
| 4,6-Dinitro-o-cresol is an uncoupler of oxidative phosphorylation. It is believed to cause an acceleration of metabolic processes that are part of the tricarboxylic ac...more Number of Targets: 4 |
| T3D0782 | 1,3-Dinitrobenzene 99-65-0 | C6H6N4O4 198.136 g/mol |  |
| In the red blood cell, 1,3-DNB induces formation of methemoglobin, leading to cyanosis. Reduction of the nitrogroup(s) of 1,3-DNB produces reactive nitroaromatic radic...more Number of Targets: 9 |
| T3D4752 | Nitrofural 59-87-0 | C6H6N4O4 198.136 g/mol |  |
| The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of gluco...more Number of Targets: 1 |
| T3D3819 | Cymoxanil 57966-95-7 | C7H10N4O3 198.179 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 5 |
| T3D4556 | Guaifenesin 93-14-1 | C10H14O4 198.216 g/mol |  |
| Guaifenesin may act as an irritant to gastric vagal receptors, and recruit efferent parasympathetic reflexes that cause glandular exocytosis of a less viscous mucus mi...more Number of Targets: 0 |
| T3D0946 | Carboxazole 55808-13-4 | C9H14N2O3 198.219 g/mol |  |
| Carboxazole is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D2798 | Metharbital 50-11-3 | C9H14N2O3 198.219 g/mol |  |
| Metharbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. ...more Number of Targets: 11 |
| T3D3775 | Slaframine 20084-93-9 | C10H18N2O2 198.262 g/mol |  |
| Slaframine is a parasympathomimetic compound and causes increased secretion by salivary glands, pancreas, and other exocrine and endocrine glands. This is due to its a...more Number of Targets: 5 |
| T3D2772 | Tacrine 321-64-2 | C13H14N2 198.264 g/mol |  |
| Tacrine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more Number of Targets: 16 |
| T3D4672 | 4,4'-Methylenedianiline 101-77-9 | C13H14N2 198.264 g/mol |  |
| After 4,4'-Methylenedianiline enters to our body, it is transported in the blood or stored in tissues. The N-N-acetylation of the compound leads to the formation of so...more Number of Targets: 3 |
| T3D1550 | Triisobutylaluminum 100-99-2 | C12H27Al 198.324 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1558 | Tri-n-butylaluminum 16-70-7 | C12H27Al 198.324 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1801 | Phenacyl bromide 70-11-1 | C8H7BrO 199.045 g/mol |  |
| Organobromide compounds such as phenacyl bromide are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of...more Number of Targets: 5 |
| T3D4080 | Dictamnine 484-29-7 | C12H9NO2 199.205 g/mol |  |
| Dictamnine has been shown to be phototoxic to human cell lines (namely Jurkat T cells and HaCaT keratinocytes). Although it is less phototoxic than the structurally re...more Number of Targets: 0 |
| T3D4532 | Pyrimethanil 53112-28-0 | C12H13N3 199.252 g/mol |  |
| Not Available Number of Targets: 11 |