Browsing Toxins By Category
Displaying toxin 1076 - 1100 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0035 | 1,2-Dibromoethane 106-93-4 | C2H4Br2 187.861 g/mol |  |
| The metabolite 2-bromoacetaldehyde produces liver damage by binding to cellular proteins. S-(2-bromoethyl)glutathione, another metabolite, exerts genotoxic and carcino...more Number of Targets: 5 |
| T3D1793 | 1,1-Dibromoethane 557-91-5 | C2H4Br2 187.861 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D1669 | 3,4-Dichlorophenyl isocyanate 102-36-3 | C7H3Cl2NO 188.011 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D3627 | 1,3-Dimethylol-5,5-dimethylhydantoin 6440-58-0 | C7H12N2O4 188.181 g/mol |  |
| DMDM hydantoin is a formaldehyde releaser. It is likely that formaldehyde toxicity occurs when intracellular levels saturate formaldehyde dehydrogenase activity, allow...more Number of Targets: 2 |
| T3D4184 | p-Cresol sulfate 3233-58-7 | C7H8O4S 188.201 g/mol |  |
| Uremic toxins such as p-Cresol sulfate are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can ...more Number of Targets: 3 |
| T3D4799 | Azelaic Acid 123-99-9 | C9H16O4 188.221 g/mol |  |
| The exact mechanism of action of azelaic acid is not known. It is thought that azelaic acid manifests its antibacterial effects by inhibiting the synthesis of cellular...more Number of Targets: 4 |
| T3D1001 | Propamocarb 24579-73-5 | C9H20N2O2 188.267 g/mol |  |
| Propamocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D4657 | P-Chlorobenzylidenemalonitrile 1867-38-5 | C10H5ClN2 188.613 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 1 |
| T3D4660 | 2-Chlorobenzylidene malononitrile 2698-41-1 | C10H5ClN2 188.613 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 1 |
| T3D0048 | Aroclor 1221 11104-28-2 | C12H9Cl 188.653 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0390 | 2-Chlorobiphenyl 2051-60-7 | C12H9Cl 188.653 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 8 |
| T3D0391 | 3-Chlorobiphenyl 2051-61-8 | C12H9Cl 188.653 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0392 | 4-Chlorobiphenyl 2051-62-9 | C12H9Cl 188.653 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 8 |
| T3D1418 | Nickelocene 1271-28-9 | C10H10Ni 188.880 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D1816 | Sodium selenate 13410-01-0 | Na2O4Se 188.940 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 4 |
| T3D0671 | Cobaltocene 1277-43-6 | C10H10Co 189.120 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D4160 | Kynurenic acid 492-27-3 | C10H7NO3 189.168 g/mol |  |
| Uremic toxins such as kynurenic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can st...more Number of Targets: 6 |
| T3D4716 | Thiotepa 52-24-4 | C6H12N3PS 189.218 g/mol |  |
| The alkyl group is attached to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring. They stop tumor growth by crosslinking guanine nucleobases...more Number of Targets: 1 |
| T3D0963 | Dipropylcarbamothioic acid S-ethyl ester 759-94-4 | C9H19NOS 189.318 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 7 |
| T3D1103 | Barium cyanide 542-62-1 | C2BaN2 189.362 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 63 |
| T3D0735 | Zinc nitrate 7779-88-6 | N2O6Zn 189.419 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 10 |
| T3D1232 | Tin(II) chloride (SnCl2) 7772-99-8 | Cl2Sn 189.620 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D1291 | Indium arsenide 1303-11-3 | AsIn 189.740 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4865 | Sodium dehydroacetate 4418-26-2 | C8H7NaO4 190.129 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0721 | Zinc antimonide 12039-35-9 | H3SbZn 190.190 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 21 |