Browsing Toxins By Category
Displaying toxin 1026 - 1050 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0279 | Arsenic trichloride 7784-34-1 | AsCl3 181.281 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0116 | 1,2,3-Trichlorobenzene 87-61-6 | C6H3Cl3 181.447 g/mol |  |
| Trichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalent...more Number of Targets: 42 |
| T3D0200 | 1,2,4-Trichlorobenzene 120-82-1 | C6H3Cl3 181.447 g/mol |  |
| Trichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalent...more Number of Targets: 39 |
| T3D0784 | 1,3,5-Trichlorobenzene 108-70-3 | C6H3Cl3 181.447 g/mol |  |
| Trichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalent...more Number of Targets: 38 |
| T3D1204 | Copper(II) acetate 142-71-2 | C4H6CuO4 181.634 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1231 | Cupriethylenediamine 13426-91-0 | C4H14CuN4 181.727 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1639 | Vanadium(V) oxide 1314-62-1 | O5V2 181.880 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1566 | Aluminum calcium sodium silicate 44-01-0 | AlCaNaO4Si 182.131 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0094 | 2,4-Dinitrotoluene 121-14-2 | C7H6N2O4 182.134 g/mol |  |
| 2,4-DNT may cause conversion of oxyhemoglobin to methemoglobin via oxidation of iron(II) to iron(III) by its metabolites. High levels of methemoglobin are removed by c...more Number of Targets: 11 |
| T3D0261 | 2,6-Dinitrotoluene 606-20-2 | C7H6N2O4 182.134 g/mol |  |
| Dinitrotoluene may cause conversion of oxyhemoglobin to methemoglobin via oxidation of iron(II) to iron(III) by its metabolites. High levels of methemoglobin are remov...more Number of Targets: 12 |
| T3D4349 | Galactitol 608-66-2 | C6H14O6 182.172 g/mol |  |
| Accumulation of galactitol in the body has been shown to be toxic. Accumulation of galactitol in the lens causes the osmotic phenomena and results in cataract formatio...more Number of Targets: 0 |
| T3D4966 | 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid 3247-75-4 | C9H10O4 182.173 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D2409 | Calcium phosphide 1305-99-3 | Ca3P2 182.182 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D1450 | Chromocene 1271-24-5 | C10H10Cr 182.183 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D4689 | Dacarbazine 4342-03-4 | C6H10N6O 182.183 g/mol |  |
| The mechanism of action is not known, but appears to exert cytotoxic effects via its action as an alkylating agent. Other theories include DNA synthesis inhibition by ...more Number of Targets: 3 |
| T3D3976 | Benzophenone 119-61-9 | C13H10O 182.218 g/mol |  |
| Benzophenone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 7 |
| T3D3990 | 3-Hydroxyfluorene 6344-67-8 | C13H10O 182.218 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D3991 | 9-Hydroxyfluorene 1689-64-1 | C13H10O 182.218 g/mol |  |
| 9-Hydroxyfluorene is a weak dopamine reuptake inhibitor. (Wikipedia) Number of Targets: 0 |
| T3D1069 | 1-(Cyclopropylmethyl)-2-(nitromethylidene)pyrrolidine 60737-54-4 | C9H14N2O2 182.220 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D0695 | Nickel nitrate 13138-45-9 | N2NiO6 182.703 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 77 |
| T3D1279 | Tin(IV) sulfide 1315-01-1 | S2Sn 182.840 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D0665 | Cobalt(II) nitrate 10141-05-6 | CoN2O6 182.943 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 44 |
| T3D3788 | Acephate 30560-19-1 | C4H10NO3PS 183.166 g/mol |  |
| Acephate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 2 |
| T3D3877 | Metam-sodium hydrate 6734-80-1 | C2H10NNaO3S2 183.225 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D2987 | Methyprylon 125-64-4 | C10H17NO2 183.248 g/mol |  |
| Methyprylon binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. ...more Number of Targets: 2 |