Browsing Toxins By Category
Displaying toxin 976 - 1000 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4174 | Guanidinosuccinic acid 6133-30-8 | C5H9N3O4 175.143 g/mol |  |
| Uremic toxins such as guanidinosuccinic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxin...more Number of Targets: 3 |
| T3D4152 | Indoleacetic acid 87-51-4 | C10H9NO2 175.184 g/mol |  |
| Uremic toxins such as indole-3-acetic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins ...more Number of Targets: 7 |
| T3D4173 | Argininic acid 157-07-3 | C6H13N3O3 175.186 g/mol |  |
| Uremic toxins such as arginic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stim...more Number of Targets: 3 |
| T3D4295 | Citrulline 372-75-8 | C6H13N3O3 175.186 g/mol |  |
| L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn responsible for citrulline's therapeutic affects. Many of L-arginine's act...more Number of Targets: 13 |
| T3D1107 | Barium fluoride 7787-32-8 | BaF2 175.324 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D1544 | Lithium tetrachloroaluminate 14024-11-4 | AlCl4Li 175.735 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1245 | Monobutyltin 78763-54-9 | C4H9Sn 175.820 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D0285 | Ammonium arsenate 7784-44-3 | AsH9N2O4 176.004 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D3521 | Metaldehyde 108-62-3 | C8H16O4 176.210 g/mol |  |
| The toxicologically active substance in metaldehyde intoxication is mainly the degradation product acetaldehyde; other toxic products are probably also formed. Acetald...more Number of Targets: 1 |
| T3D3956 | Cotinine 486-56-6 | C10H12N2O 176.215 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1565 | Bis(isobutyl)aluminum chloride 1779-25-5 | C8H18AlCl 176.663 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0653 | Cobalt(II) acetate 71-48-7 | C4H6CoO4 177.021 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D4215 | N'-nitrosonornicotine 16543-55-8 | C9H11N3O 177.203 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D2904 | Phenmetrazine 134-49-6 | C11H15NO 177.243 g/mol |  |
| Phenmetrazine is thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron leading to an increase in the release of these monoamines int...more Number of Targets: 3 |
| T3D1576 | Palladium(II) chloride 7647-10-1 | Cl2Pd 177.330 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1789 | N-Bromosuccinimide 128-08-5 | C4H4BrNO2 177.984 g/mol |  |
| Organobromide compounds such as n-Bromosuccinimide are strong alkylating agents. Consequently they can readily modify free thiols (cysteines), methionines as well as ...more Number of Targets: 1 |
| T3D0301 | Arsenobetaine 64436-13-1 | C5H11AsO2 178.061 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D2990 | Phenacemide 63-98-9 | C9H10N2O2 178.188 g/mol |  |
| Phenacemide binds to and blocks neuronal sodium channels or voltage sensitive calcium channels. This blocks or suppresses neuronal depolarization and hypersynchronizat...more Number of Targets: 1 |
| T3D4876 | Methyleugenol 93-15-2 | C11H14O2 178.228 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0246 | Phenanthrene 85-01-8 | C14H10 178.229 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 6 |
| T3D0619 | Anthracene 120-12-7 | C14H10 178.229 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D2900 | Propofol 2078-54-8 | C12H18O 178.271 g/mol |  |
| The action of propofol involves a positive modulation of the inhibitory function of the neurotransmitter gama-aminobutyric acid (GABA) through GABA-A receptors. Number of Targets: 11 |
| T3D1244 | Monobutyltin hydride 2406-65-7 | C4H12Sn 178.850 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1262 | Tetramethyltin 594-27-4 | C4H12Sn 178.850 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D4159 | Hippuric acid 495-69-2 | C9H9NO3 179.173 g/mol |  |
| Uremic toxins such as hippuric acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can sti...more Number of Targets: 4 |