Browsing Toxins By Category
Displaying toxin 1951 - 1975 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0426 | 3,4,4'-Trichlorobiphenyl 38444-90-5 | C12H7Cl3 257.543 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0427 | 3,4,5-Tricholobiphenyl 53555-66-1 | C12H7Cl3 257.543 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0428 | 3,4',5-Trichlorobiphenyl 38444-88-1 | C12H7Cl3 257.543 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D3938 | Trichlorfon 52-68-6 | C4H8Cl3O4P 257.437 g/mol |  |
| Trichlorfon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 6 |
| T3D2914 | Levorphanol 77-07-6 | C17H23NO 257.371 g/mol |  |
| Like other mu-agonist opioids it is believed to act at receptors in the periventricular and periaqueductal gray matter in both the brain and spinal cord to alter the t...more Number of Targets: 3 |
| T3D0982 | Methiocarb sulfone 2179-25-1 | C11H15NO4S 257.306 g/mol |  |
| Methiocarb sulfone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the acti...more Number of Targets: 2 |
| T3D0808 | Paraquat dichloride 1910-42-5 | C12H14Cl2N2 257.159 g/mol |  |
| The mechanisms of the toxic effects of paraquat are largely the result of a metabolically catalyzed single electron oxidation reduction reaction, resulting in depletio...more Number of Targets: 4 |
| T3D1862 | Antimony(III) ethoxide 10433-06-4 | C6H15O3Sb 256.940 g/mol |  |
| The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes ...more Number of Targets: 20 |
| T3D1620 | Silver trifluoromethanesulfonate 1493-13-6 | CAgF3O3S 256.937 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D4545 | Triclopyr 55335-06-3 | C7H4Cl3NO3 256.471 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4797 | Palmitic acid 57-10-3 | C16H32O2 256.424 g/mol |  |
| Not Available Number of Targets: 19 |
| T3D4006 | Mono-benzyl phthalate 2528-16-7 | C15H12O4 256.253 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4530 | Propyzamide 23950-58-5 | C12H11Cl2NO 256.128 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D2570 | Lamotrigine 84057-84-1 | C9H7Cl2N5 256.091 g/mol |  |
| One proposed mechanism of action of Lamotrigine, the relevance of which remains to be established in humans, involves an effect on sodium channels. in vitro pharmacolo...more Number of Targets: 10 |
| T3D0797 | Imidacloprid 105827-78-9 | C9H10ClN5O2 255.661 g/mol |  |
| Imidacloprid acts on the nicotinic acetylcholine receptor; the chlorination inhibits degradation by acetylcholine-esterase (L1130). Number of Targets: 12 |
| T3D0803 | 2,4,5-Trichlorophenoxyacetic acid 93-76-5 | C8H5Cl3O3 255.483 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 3 |
| T3D2976 | Diphenhydramine 58-73-1 | C17H21NO 255.355 g/mol |  |
| Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the...more Number of Targets: 8 |
| T3D2737 | Atomoxetine 82248-59-7 | C17H21NO 255.355 g/mol |  |
| The precise mechanism by which atomoxetine produces its therapeutic effects in Attention-Deficit/Hyperactivity Disorder (ADHD) is unknown, but is thought to be related...more Number of Targets: 6 |
| T3D1308 | Diphenylcyanoarsine 23525-22-6 | C13H10AsN 255.147 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 46 |
| T3D3848 | Fluroxypyr 69377-81-7 | C7H5Cl2FN2O3 255.031 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D1751 | Selenium oxybromide 7789-51-7 | Br2OSe 254.770 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 6 |
| T3D0374 | Cadmium fluosilicate 17010-21-8 | CdF6Si 254.487 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 19 |
| T3D3079 | Djenkolic acid 498-59-9 | C7H14N2O4S2 254.327 g/mol |  |
| The toxicity of djenkolic acid in humans arises from its poor solubility under acidic conditions after consumption of the jenkol bean. The amino acid precipitates into...more Number of Targets: 0 |
| T3D3694 | Elymoclavine 548-43-6 | C16H18N2O 254.327 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 6 |
| T3D3695 | Lysergol 602-85-7 | C16H18N2O 254.327 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 10 |