Browsing Toxins By Category
Displaying toxin 1701 - 1725 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2528 | Histrionicotoxin 34272-51-0 | C19H25NO 283.408 g/mol |  |
| Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1072) Number of Targets: 16 |
| T3D3855 | Fosthiazate 98886-44-3 | C9H18NO3PS2 283.348 g/mol |  |
| Fosthiazate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 10 |
| T3D1337 | Basic lead acetate 51404-69-4 | C2H4O3Pb 283.300 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D4175 | 8-Hydroxy-deoxyguanosine 88847-89-6 | C10H13N5O5 283.241 g/mol |  |
| Uremic toxins such as 8-Hydroxy-2Х-deoxyguanosine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic ...more Number of Targets: 4 |
| T3D1428 | Chromium(III) potassium sulfate 10141-00-1 | CrKO8S2 283.220 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D2668 | Risedronate 105462-24-6 | C7H11NO7P2 283.112 g/mol |  |
| The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Risedronate also targets farn...more Number of Targets: 3 |
| T3D0289 | Copper arsenate hydroxide 16102-92-4 | AsCu2HO5 283.019 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 49 |
| T3D1607 | Silver iodate 7783-97-3 | AgIO3 282.771 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D1559 | Tri-n-hexylaluminum 1116-73-0 | C18H39Al 282.484 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4802 | Oleic acid 112-80-1 | C18H34O2 282.461 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4831 | Octyl gallate 1034-01-1 | C15H22O5 282.332 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D1241 | Monobutyltin trichloride 1118-46-3 | C4H9Cl3Sn 282.180 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1875 | Nitronium hexafluoroantimonate(V) 17856-92-7 | F6NO2Sb 281.760 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1589 | Dichloro(1,5-cyclooctadiene) palladium(II) 12107-56-1 | C8H8Cl2Pd 281.480 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1340 | Ethyltrimethyl lead 1762-26-1 | C5H14Pb 281.400 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D0716 | Zinc dichromate 14018-95-2 | Cr2O7Zn 281.397 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 6 |
| T3D3909 | Propetamphos 31218-83-4 | C10H20NO4PS 281.309 g/mol |  |
| Propetamphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 26 |
| T3D0890 | Pendimethalin 40487-42-1 | C13H19N3O4 281.308 g/mol |  |
| Inhibits cell division and cell elongation (L800). Number of Targets: 8 |
| T3D3057 | Nitrazepam 146-22-5 | C15H11N3O3 281.266 g/mol |  |
| Nitrazepam belongs to a group of medicines called benzodiazepines. It acts on benzodiazepine receptors in the brain which are associated with the GABA receptors causin...more Number of Targets: 24 |
| T3D0904 | 3-Iodo-2-propynyl butyl carbamate 55406-53-6 | C8H12INO2 281.091 g/mol |  |
| 3-Iodo-2-propynyl butyl carbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylat...more Number of Targets: 16 |
| T3D4928 | Linoleic acid 60-33-3 | C18H32O2 280.446 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D2797 | Imipramine 50-49-7 | C19H24N2 280.407 g/mol |  |
| Imipramine works by inhibiting the neuronal reuptake of the neurotransmitters norepinephrine and serotonin. It binds the sodium-dependent serotonin transporter and sod...more Number of Targets: 34 |
| T3D3105 | Phenprocoumon 435-97-2 | C18H16O3 280.318 g/mol |  |
| Phenprocoumon inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of ...more Number of Targets: 3 |
| T3D4955 | 2,3,6,9-Tetrachlorodecane Not Available | C10H18Cl4 280.062 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2986 | Sibutramine 106650-56-0 | C17H26ClN 279.848 g/mol |  |
| Sibutramine produces its therapeutic effects by inhibition of norepinephrine (NE), serotonin (5-hydroxytryptamine, 5-HT), and to a lesser extent, dopamine reuptake at ...more Number of Targets: 6 |