Browsing Toxins By Category
Displaying toxin 1676 - 1700 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1792 | 1,3-Dibromo-5,5-dimethylhydantoin 77-48-5 | C5H6Br2N2O2 285.921 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 1 |
| T3D1250 | Triethyltin bromide 2767-54-6 | C6H15BrSn 285.800 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 18 |
| T3D4774 | Cladribine 4291-63-8 | C10H12ClN5O3 285.687 g/mol |  |
| Cladribine is structurally related to fludarabine and pentostatin but has a different mechanism of action. Although the exact mechanism of action has not been fully de...more Number of Targets: 14 |
| T3D2325 | 6-Methyl-1,3,8-trichlorodibenzofuran 118174-38-2 | C13H7Cl3O 285.553 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 3 |
| T3D4950 | Tris(2-chloroethyl)phosphate 115-96-8 | C6H12Cl3O4P 285.490 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1393 | cis-Dichlorobis(ethylenediamine)cobalt(III) chloride 14040-32-5 | C4H16Cl3CoN4 285.489 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1394 | trans-Dichlorobis(ethylenediamine)cobalt(III) chloride 14040-33-6 | C4H16Cl3CoN4 285.489 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D2850 | Pentazocine 359-83-1 | C19H27NO 285.424 g/mol |  |
| The preponderance of evidence suggests that pentazocine antagonizes the opioid effects by competing for the same receptor sites, especially the opioid mu receptor. Number of Targets: 4 |
| T3D2740 | Morphine 57-27-2 | C17H19NO3 285.338 g/mol |  |
| The precise mechanism of the analgesic action of morphine is unknown. However, specific CNS opiate receptors have been identified and likely play a role in the express...more Number of Targets: 10 |
| T3D2752 | Hydromorphone 466-99-9 | C17H19NO3 285.338 g/mol |  |
| Hydromorphone is a narcotic analgesic; its principal therapeutic effect is relief of pain. Hydromorphone interacts predominantly with the opioid mu-receptors. These mu...more Number of Targets: 3 |
| T3D4803 | Letrozole 112809-51-5 | C17H11N5 285.303 g/mol |  |
| Letrozole is a nonsteroidal competitive inhibitor of the aromatase enzyme system; it inhibits the conversion of androgens to estrogens. In adult nontumor- and tumorbea...more Number of Targets: 2 |
| T3D0093 | Hexachlorobenzene 118-74-1 | C6Cl6 284.782 g/mol |  |
| Hexachlorobenzene causes porphyria by modifying sulfhydryl groups in the catalytic or substrate-binding sites of uroporphyrinogen decarboxylase. This inhibits uroporph...more Number of Targets: 43 |
| T3D2830 | Mazindol 22232-71-9 | C16H13ClN2O 284.740 g/mol |  |
| Although the mechanism of action of the sympathomimetics in the treatment of obesity is not fully known, these medications have pharmacological effects similar to thos...more Number of Targets: 4 |
| T3D2903 | Diazepam 439-14-5 | C16H13ClN2O 284.740 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors which mediate sleep, affects muscle relaxation, anticonvulsant activity, motor coordination, and memor...more Number of Targets: 24 |
| T3D0340 | Mercury(II) fulminate 628-86-4 | C2HgN2O2 284.620 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D4814 | Cetyl-Trimethyl-Ammonium 57-09-0 | C19H42N 284.543 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4755 | Stearic acid 57-11-4 | C18H36O2 284.477 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D4560 | Promethazine 60-87-7 | C17H20N2S 284.419 g/mol |  |
| Like other H1-antagonists, promethazine competes with free histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscl...more Number of Targets: 13 |
| T3D2565 | Promazine 58-40-2 | C17H20N2S 284.419 g/mol |  |
| Promazine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine ...more Number of Targets: 16 |
| T3D1582 | Ammonium tetrachloro-palladate(II) 19168-23-1 | Cl4H8N2Pd 284.310 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1763 | Thallium(I) bromide 7789-40-4 | BrTl 284.287 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D4886 | Biochanin A 491-80-5 | C16H12O5 284.264 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D2457 | Psilocybin 520-52-5 | C12H17N2O4P 284.248 g/mol |  |
| Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the e...more Number of Targets: 3 |
| T3D1089 | Metolachlor 51218-45-2 | C15H22ClNO2 283.794 g/mol |  |
| Metolachlor acts by inhibition of elongases and of the geranylgeranyl pyrophosphate (GGPP) cyclases, which are part of the gibberellin pathway. It also binds to nAChRs...more Number of Targets: 26 |
| T3D3620 | Ammonium lauryl sulfate 2235-54-3 | C12H29NO4S 283.428 g/mol |  |
| While ammonium lauryl sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosa...more Number of Targets: 2 |