
Browsing Toxins By Category
Displaying toxin 1476 - 1500 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D2877 | Scopolamine 51-34-3 | C17H21NO4 303.353 g/mol | ![]() |
| Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center). Number of Targets: 6 |
T3D2927 | Cocaine 50-36-2 | C17H21NO4 303.353 g/mol | ![]() |
| Cocaine produces anesthesia by inhibiting excitation of nerve endings or by blocking conduction in peripheral nerves. This is achieved by reversibly binding to and ina...more Number of Targets: 15 |
T3D0335 | Lead sulfate 7446-14-2 | O4PbS 303.300 g/mol | ![]() |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
T3D1156 | Zinc permanganate 23414-72-4 | Mn2O8Zn 303.280 g/mol | ![]() |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 6 |
T3D3811 | Clofentezine 74115-24-5 | C14H8Cl2N4 303.146 g/mol | ![]() |
| Not Available Number of Targets: 15 |
T3D1791 | Broxyquinoline 521-74-4 | C9H5Br2NO 302.950 g/mol | ![]() |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
T3D4570 | Fludiazepam 3900-31-0 | C16H12ClFN2O 302.731 g/mol | ![]() |
| Fludiazepam has similar action to diazepam, but binds with four times more affinity to benzodiazepine receptors than diazepam. Number of Targets: 18 |
T3D4748 | Methyltestosterone 58-18-4 | C20H30O2 302.451 g/mol | ![]() |
| The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by co...more Number of Targets: 4 |
T3D1024 | Allethrin 584-79-2 | C19H26O3 302.408 g/mol | ![]() |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 36 |
T3D3920 | S-Bioallethrin 28434-00-6 | C19H26O3 302.408 g/mol | ![]() |
| Not Available Number of Targets: 20 |
T3D4813 | Masoprocol 500-38-9 | C18H22O4 302.365 g/mol | ![]() |
| Although the exact mechanism of action is not known, studies have shown that masoprocol is a potent 5-lipoxygenase inhibitor and has antiproliferative activity against...more Number of Targets: 9 |
T3D3879 | Methidathion 950-37-8 | C6H11N2O4PS3 302.331 g/mol | ![]() |
| Methidathion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 15 |
T3D4758 | Quercetin 117-39-5 | C15H10O7 302.236 g/mol | ![]() |
| Quercetin is a specific quinone reductase 2 (QR2) inhibitor, an enzyme (along with the human QR1 homolog) which catalyzes metabolism of toxic quinolines. Inhibition of...more Number of Targets: 12 |
T3D3838 | Fenhexamid 126833-17-8 | C14H17Cl2NO2 302.196 g/mol | ![]() |
| Not Available Number of Targets: 7 |
T3D2770 | Trihexyphenidyl 144-11-6 | C20H31NO 301.466 g/mol | ![]() |
| Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or neuronal) and the peripheral mus...more Number of Targets: 5 |
T3D0969 | Fenoxycarb 72490-01-8 | C17H19NO4 301.337 g/mol | ![]() |
| Fenoxycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 11 |
T3D3015 | Oxymorphone 76-41-5 | C17H19NO4 301.337 g/mol | ![]() |
| Oxymorphone interacts predominantly with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, with high densities in the poste...more Number of Targets: 3 |
T3D1224 | Copper(II) pyrophosphate 10102-90-6 | Cu2O7P2 301.035 g/mol | ![]() |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
T3D4564 | Clobazam 22316-47-8 | C16H13ClN2O2 300.740 g/mol | ![]() |
| Clobazam binds at distinct binding sites associated with the chloride ionopore at the post-synaptic GABA receptor. These GABA receptors are in various locations in the...more Number of Targets: 18 |
T3D2719 | Temazepam 846-50-4 | C16H13ClN2O2 300.740 g/mol | ![]() |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodia...more Number of Targets: 21 |
T3D3804 | Captan 133-06-2 | C9H8Cl3NO2S 300.589 g/mol | ![]() |
| Not Available Number of Targets: 19 |
T3D2884 | 9-cis-Retinoic acid 302-79-4 | C20H28O2 300.435 g/mol | ![]() |
| Tretinoin binds to alpha, beta, and gamma retinoic acid receptors (RARs). RAR-alpha and RAR-beta have been associated with the development of acute promyelocytic leuke...more Number of Targets: 25 |
T3D4526 | Prallethrin 23031-36-9 | C19H24O3 300.392 g/mol | ![]() |
| Not Available Number of Targets: 21 |
T3D3798 | Bifenazate 149877-41-8 | C17H20N2O3 300.352 g/mol | ![]() |
| Not Available Number of Targets: 17 |
T3D0624 | Coronene 191-07-1 | C24H12 300.352 g/mol | ![]() |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |