Browsing Toxins By Category
Displaying toxin 1401 - 1425 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4533 | Quinoxyfen 124495-18-7 | C15H8Cl2FNO 308.135 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D1166 | Uranium peroxide 12036-71-4 | H6O4U 308.074 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D1127 | Yttrium barium copper oxide 107539-20-8 | BaCuH2OY 307.794 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 27 |
| T3D2724 | Benzatropine 86-13-5 | C21H25NO 307.429 g/mol |  |
| Benztropine is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or neuronal) and the peripheral muscari...more Number of Targets: 3 |
| T3D2787 | Zolpidem 82626-48-0 | C19H21N3O 307.390 g/mol |  |
| Zolpidem modulates the alpha-subunit, known as the benzodiazepine receptor, within the GABAA receptor chloride channel macromolecular complex. Unlike the benzodiazepin...more Number of Targets: 7 |
| T3D4352 | Glutathione 70-18-8 | C10H17N3O6S 307.323 g/mol |  |
| Glutathione (GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase. It is also important as a hydrophilic molecule that is...more Number of Targets: 42 |
| T3D1782 | Bromodeoxyuridine 59-14-3 | C9H11BrN2O5 307.098 g/mol |  |
| 5-bromodeoxyuridine acts on DNA. It induces a random DNA point mutation via base substitution. The base pair will change from an A-T to a G-C or from a G-C to an A-T a...more Number of Targets: 3 |
| T3D3654 | Di-n-pentyl phthalate 131-18-0 | C18H26O4 306.397 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 9 |
| T3D2711 | Fluconazole 86386-73-4 | C13H12F2N6O 306.271 g/mol |  |
| Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fu...more Number of Targets: 4 |
| T3D1314 | Triphenylarsine 603-32-7 | C18H15As 306.233 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D2985 | Sertraline 79617-96-2 | C17H17Cl2N 306.230 g/mol |  |
| The exact mechanism of action sertraline is not fully known, but the drug appears to selectively inhibit the reuptake of serotonin at the presynaptic membrane. This re...more Number of Targets: 9 |
| T3D2152 | 1,2,3,4-Tetrachlorodibenzofuran 24478-72-6 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2161 | 1,2,3,6-Tetrachlorodibenzofuran 83704-21-6 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2167 | 1,2,3,7-Tetrachlorodibenzofuran 83704-22-7 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2169 | 1,2,3,8-Tetrachlorodibenzofuran 62615-08-1 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2170 | 1,2,3,9-Tetrachlorodibenzofuran 83704-23-8 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2177 | 1,2,4,6-Tetrachlorodibenzofuran 71998-73-7 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2180 | 1,2,4,7-Tetrachlorodibenzofuran 83719-40-8 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2182 | 1,2,4,8-Tetrachlorodibenzofuran 64126-87-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2186 | 1,2,6,7-Tetrachlorodibenzofuran 83704-25-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2187 | 1,2,6,8-Tetrachlorodibenzofuran 83710-07-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2189 | 1,2,7,8-Tetrachlorodibenzofuran 58802-20-3 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2190 | 1,2,7,9-Tetrachlorodibenzofuran 83704-26-1 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2197 | 1,3,4,6-Tetrachlorodibenzofuran 83704-27-2 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2200 | 1,3,4,7-Tetrachlorodibenzofuran 70648-16-7 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |