Browsing Toxins By Category
Displaying toxin 1351 - 1375 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1354 | Phenylmercuric chloride 100-56-1 | C6H5ClHg 313.150 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 51 |
| T3D1114 | Barium iron oxide 12047-11-9 | BaFe2O4 313.015 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D0661 | Cobalt(II) iodide 15238-00-3 | CoI2 312.742 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D4454 | Phytanic acid 14721-66-5 | C20H40O2 312.530 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0694 | Nickel iodide 13462-90-3 | I2Ni 312.502 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D4749 | Levonorgestrel 797-63-7 | C21H28O2 312.446 g/mol |  |
| Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once boun...more Number of Targets: 7 |
| T3D2754 | Olanzapine 132539-06-1 | C17H20N4S 312.433 g/mol |  |
| Olanzapine's antipsychotic activity is likely due to a combination of antagonism at D2 receptors in the mesolimbic pathway and 5HT2A receptors in the frontal cortex. A...more Number of Targets: 36 |
| T3D3558 | Cellulose nitrate 9004-70-0 | C20H16N4 312.368 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D0195 | Benzyl butyl phthalate 85-68-7 | C19H20O4 312.360 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 11 |
| T3D3674 | Nivalenol 23282-20-4 | C15H20O7 312.315 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3598 | Aflatoxin B1 1162-65-8 | C17H12O6 312.274 g/mol |  |
| Aflatoxin B1 requires epoxidation to aflatoxin B1 2,3-oxide for activation, which is performed by cytochome P-450 enzymes CYP1A2 and CYP3A4. It produces DNA damage, ge...more Number of Targets: 11 |
| T3D1818 | Diphenyl diselenide 1666-13-3 | C12H10Se2 312.130 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D1918 | 2,3-Dibromobiphenyl 115245-06-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1939 | 2,2'-Dibromobiphenyl 13029-09-9 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1941 | 3,5-Dibromobiphenyl 16372-96-6 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1943 | 3,3'-Dibromobiphenyl 16400-51-4 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1954 | 2,3'-Dibromobiphenyl 49602-90-6 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1955 | 2,4'-Dibromobiphenyl 49602-91-7 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1957 | 2,4-Dibromobiphenyl 53592-10-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1960 | 3,4'-Dibromobiphenyl 57186-90-0 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1961 | 2,5-Dibromobiphenyl 57422-77-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1962 | 2,6-Dibromobiphenyl 59080-32-9 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1977 | 3,4-Dibromobiphenyl 60108-72-7 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2019 | 4,4'-Dibromobiphenyl 92-86-4 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1087 | Butachlor 23184-66-9 | C17H26ClNO2 311.847 g/mol |  |
| Binds to nAChRs in nervous systems. Also causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (T10, A590) Number of Targets: 35 |