Browsing Toxins By Category
Displaying toxin 1151 - 1175 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3718 | Trichothecin 6379-69-7 | C19H24O5 332.391 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3702 | Crotocin 21284-11-7 | C19H24O5 332.391 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D4022 | Sanguinarine 2447-54-3 | C20H14NO4 332.329 g/mol |  |
| Sanguinarine, at micromolar concentrations, imparts cell growth inhibitory response in human squamous carcinoma (A431) cells via an induction of apoptosis. This is whi...more Number of Targets: 0 |
| T3D4808 | Fluorescein 2321-07-5 | C20H12O5 332.306 g/mol |  |
| Fluorescein sodium is used extensively as a diagnostic tool in the field of ophthalmology. Fluorescein is a fluorescent compound or fluorophore having a maximum absorb...more Number of Targets: 6 |
| T3D0709 | Silver chromate 7784-01-2 | Ag2CrO4 331.730 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 21 |
| T3D1881 | Silver(I) hexafluoroantimonate 26042-64-8 | AgH6O6Sb 331.670 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 37 |
| T3D1762 | Tetrabromomethane 558-13-4 | CBr4 331.627 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1028 | Tetramethrin 7696-12-0 | C19H25NO4 331.406 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 28 |
| T3D3495 | Ciprofloxacin 85721-33-1 | C17H18FN3O3 331.342 g/mol |  |
| The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DN...more Number of Targets: 3 |
| T3D2339 | Cercosporamide 131436-22-1 | C16H13NO7 331.277 g/mol |  |
| Dibenzofurans bind the aryl hydrocarbon receptor, which increases its ability to activate transcription in the XRE promoter region. This alters the expression of a num...more Number of Targets: 6 |
| T3D0329 | Lead nitrate 10099-74-8 | N2O6Pb 331.200 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 38 |
| T3D4505 | Fenarimol 60168-88-9 | C17H12Cl2N2O 331.196 g/mol |  |
| Fenarimol is an antiandrogen. It has effects on the reproductive organs and prostate gene expression levels. Studies suggested that the adverse effects of Fenarimol in...more Number of Targets: 23 |
| T3D4804 | 2,4,6-Tribromophenol 118-79-6 | C6H3Br3O 330.799 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4282 | 17-Hydroxyprogesterone 68-96-2 | C21H30O3 330.461 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D4245 | Deoxycorticosterone 64-85-7 | C21H30O3 330.461 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D2338 | Cannabielsoin 52025-76-0 | C21H30O3 330.461 g/mol |  |
| Dibenzofurans bind the aryl hydrocarbon receptor, which increases its ability to activate transcription in the XRE promoter region. This alters the expression of a num...more Number of Targets: 4 |
| T3D1855 | Jasmolin I 4466-14-2 | C21H30O3 330.461 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D3643 | Dicyclohexyl phthalate 84-61-7 | C20H26O4 330.418 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 6 |
| T3D3870 | Malathion 121-75-5 | C10H19O6PS2 330.358 g/mol |  |
| Malathion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 16 |
| T3D3672 | Aflatoxin M2 6885-57-0 | C17H14O7 330.289 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 3 |
| T3D3866 | Iprodione 36734-19-7 | C13H13Cl2N3O3 330.167 g/mol |  |
| Not Available Number of Targets: 19 |
| T3D3935 | Tralkoxydim 87820-88-0 | C20H27NO3 329.433 g/mol |  |
| Tralkoxydim is structurally a cyclohexanedione, but because it does not appear to produce a toxic metabolite produced by other substances, the EPA has not assumed that...more Number of Targets: 5 |
| T3D2868 | Paroxetine 61869-08-7 | C19H20FNO3 329.365 g/mol |  |
| Paroxetine is a potent and highly selective inhibitor of neuronal serotonin reuptake. Paroxetine likely inhibits the reuptake of serotonin at the neuronal membrane, en...more Number of Targets: 17 |
| T3D0952 | Cypendazole 28559-00-4 | C16H19N5O3 329.354 g/mol |  |
| Cypendazole is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D0762 | Potassium ferricyanide 13746-66-2 | C6FeK3N6 329.244 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |