Browsing Toxins By Category
Displaying toxin 1101 - 1125 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3686 | Methylergonovine 113-42-8 | C20H25N3O2 339.431 g/mol |  |
| Ergoline alkaloids have been shown to have the significant affinity towards the 5-HT1 and 5-HT2 serotonin receptors, D1 and D2 dopamine receptors, and alpha-adrenergic...more Number of Targets: 4 |
| T3D4103 | Nantenine 2565-01-7 | C20H21NO4 339.385 g/mol |  |
| Nantenine is an antagonist at both the α1 adrenergic receptor and the 5-HT2A serotonin receptor, and blocks both the behavioural and physiological effects of MDMA in a...more Number of Targets: 37 |
| T3D4092 | Dicentrine 517-66-8 | C20H21NO4 339.385 g/mol |  |
| Dicentrine was found to be a potent alpha 1-adrenoceptor blocking agent in rat thoracic aorta as revealed by its competitive antagonism of noradrenaline- (pA2 = 8.19 +...more Number of Targets: 2 |
| T3D0929 | Benthiavalicarb 413615-35-7 | C15H18FN3O3S 339.385 g/mol |  |
| Benthiavalicarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active ...more Number of Targets: 2 |
| T3D2733 | Topiramate 97240-79-4 | C12H21NO8S 339.362 g/mol |  |
| The precise mechanism of action of topiramate is not known. However, studies have shown that topiramate blocks the action potentials elicited repetitively by a sustain...more Number of Targets: 9 |
| T3D1552 | Methyl aluminum sesquibromide 12263-85-3 | C3H9Al2Br3 338.779 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 9 |
| T3D1363 | Phenylmercuric borate 102-98-7 | C6H7BHgO3 338.520 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D1844 | Bioresmethrin 28434-01-7 | C22H26O3 338.440 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 19 |
| T3D1027 | Resmethrin 10453-86-8 | C22H26O3 338.440 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 30 |
| T3D1025 | Cismethrin 35764-59-1 | C22H26O3 338.440 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 19 |
| T3D4904 | Dodecyl gallate 1166-52-5 | C19H30O5 338.439 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4524 | Piperonyl butoxide 51-03-6 | C19H30O5 338.439 g/mol |  |
| Not Available Number of Targets: 19 |
| T3D0834 | Bergamottin 7380-40-7 | C21H22O4 338.397 g/mol |  |
| Bergamottin is a potent chemopreventive agent against aflatoxin B1-inducible cyotoxicity in H4IIE cells with a bifunctional effects on glutathione S-transferase and CY...more Number of Targets: 3 |
| T3D3701 | 15-Acetyl-4-deoxynivalenol 88337-96-6 | C17H22O7 338.352 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3700 | Acetyldeoxynivalenol 50722-38-8 | C17H22O7 338.352 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D1254 | Mono-n-octyltin trichloride 3091-25-6 | C8H17Cl3Sn 338.290 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D2886 | Olopatadine 113806-05-6 | C21H23NO3 337.412 g/mol |  |
| Olopatadine is a selective histamine H1 antagonist that binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to...more Number of Targets: 6 |
| T3D2675 | Linezolid 165800-03-3 | C16H20FN3O4 337.346 g/mol |  |
| Linezolid targets the large 39S subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result Linezolid is cytotoxic to the m...more Number of Targets: 6 |
| T3D4506 | Fenbuconazole 114369-43-6 | C19H17ClN4 336.818 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 16 |
| T3D0344 | Phenylmercuric acetate 62-38-4 | C8H8HgO2 336.740 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 98 |
| T3D4550 | Zoxamide 156052-68-5 | C14H16Cl3NO2 336.641 g/mol |  |
| Not Available Number of Targets: 29 |
| T3D2898 | Fentanyl 437-38-7 | C22H28N2O 336.471 g/mol |  |
| Opiate receptors are coupled with G-protein receptors and function as both positive and negative regulators of synaptic transmission via G-proteins that activate effec...more Number of Targets: 5 |
| T3D3010 | Fluoxymesterone 76-43-7 | C20H29FO3 336.441 g/mol |  |
| Fluoxymesterone is a synthetic androgenic anabolic steroid and is approximately 5 times as potent as natural methyltestosterone. Like testosterone and other androgenic...more Number of Targets: 5 |
| T3D1452 | Ammonium tetrathiocyanato-diamminechromate(III) 13573-16-5 | C4H10CrN7S4 336.425 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 44 |
| T3D3736 | Cyclopiazonic acid 18172-33-3 | C20H20N2O3 336.384 g/mol |  |
| Cyclopiazonic acid is potent and specific inhibitor of the endoplasmic and sarcoplasmic reticulum Ca+-dependent ATPases, which are essential for calcium reuptake in th...more Number of Targets: 9 |