Browsing Toxins By Category
Displaying toxin 1001 - 1025 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4696 | Griseofulvin 126-07-8 | C17H17ClO6 352.766 g/mol |  |
| Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis an...more Number of Targets: 1 |
| T3D2893 | Halazepam 23092-17-3 | C17H12ClF3N2O 352.738 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D4738 | Encainide 66778-36-7 | C22H28N2O2 352.470 g/mol |  |
| Encainide is a sodium channel blocker, binding to voltage gated sodium channels. It stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the in...more Number of Targets: 1 |
| T3D3925 | Tebufenozide 112410-23-8 | C22H28N2O2 352.470 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D2929 | Anileridine 144-14-9 | C22H28N2O2 352.470 g/mol |  |
| Opiate receptors are coupled with G-protein receptors and function as both positive and negative regulators of synaptic transmission via G-proteins that activate effec...more Number of Targets: 1 |
| T3D3091 | Grayanotoxin II 4678-44-8 | C20H32O5 352.465 g/mol |  |
| Grayanotoxins bind to specific sodium ion channels in cell membranes. The grayanotoxins prevent inactivation, leaving excitable cells depolarized. (L1251) Number of Targets: 14 |
| T3D2813 | Triflupromazine 146-54-3 | C18H19F3N2S 352.417 g/mol |  |
| Triflupromazine binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. The mechanism of the anti-emetic effect is due predominantly to blockag...more Number of Targets: 6 |
| T3D3729 | Altertoxin-1 56258-32-3 | C20H16O6 352.337 g/mol |  |
| Altertoxin-1 has been shown to have genotoxic and mutagenic properties. It has demonstrated DNA-damaging activities such as single-strand and double-strand DNA breaks,...more Number of Targets: 4 |
| T3D1164 | Uranium hexafluoride 7783-81-5 | F6U 352.019 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D2899 | Meloxicam 71125-38-7 | C14H13N3O4S2 351.401 g/mol |  |
| Anti-inflammatory effects of meloxicam are believed to be due to inhibition of prostaglandin synthetase (cylooxygenase), leading to the inhibition of prostaglandin syn...more Number of Targets: 2 |
| T3D1282 | Dibutyltin diacetate 1067-33-0 | C12H24O4Sn 351.030 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1263 | Triphenyltin hydride 892-20-6 | C18H16Sn 351.030 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D0293 | Magnesium arsenate 10103-50-1 | As2Mg3O8 350.753 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 |
| T3D0127 | Chlorpyrifos 2921-88-2 | C9H11Cl3NO3PS 350.586 g/mol |  |
| Chlorpyrifos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 55 |
| T3D3907 | Propargite 2312-35-8 | C19H26O4S 350.472 g/mol |  |
| Not Available Number of Targets: 41 |
| T3D1026 | Phenothrin 26002-80-2 | C23H26O3 350.451 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 21 |
| T3D2330 | 8-Bromo-2,3,4-trichlorodibenzofuran 103124-72-7 | C12H4BrCl3O 350.423 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D3706 | Diacetylverrucarol 2198-94-9 | C19H26O6 350.406 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D4527 | Prodiamine 29091-21-2 | C13H17F3N4O4 350.294 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D1251 | Triphenyltin 668-34-8 | C18H15Sn 350.020 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D4486 | Clodinafop-propargyl 105512-06-9 | C17H13ClFNO4 349.741 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D1846 | Fenpropathrin 39515-41-8 | C22H23NO3 349.423 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 32 |
| T3D1438 | Chromium(III) acetylacetonate 21679-31-2 | C15H21CrO6 349.320 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D4569 | Cloxazolam 24166-13-0 | C17H14Cl2N2O2 349.211 g/mol |  |
| Cloxazolam is a long acting benzodiazepine. It acts as a prodrug, with pharmacologically active metabolites, which bind to to the GABAa receptor, which other benzodiaz...more Number of Targets: 18 |
| T3D4482 | Captafol 2425-06-1 | C10H9Cl4NO2S 349.061 g/mol |  |
| Not Available Number of Targets: 21 |