Browsing Toxins By Category
Displaying toxin 951 - 975 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1854 | Cinerin II 121-20-0 | C21H28O5 360.444 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D3829 | Difenzoquat metilsulfate 43222-48-6 | C18H20N2O4S 360.427 g/mol |  |
| Difenzoquat metilsulfate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of ac...more Number of Targets: 21 |
| T3D0353 | Mercury(II) bromide 7789-47-1 | Br2Hg 360.400 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 56 |
| T3D1771 | Zirconium(IV) bromide 1377-25-8 | C16H19F3N2O4 360.328 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1591 | Palladium(II) iodide 90-38-7 | I2Pd 360.230 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D3834 | Etoxazole 153233-91-1 | C21H23F2NO2 359.410 g/mol |  |
| Not Available Number of Targets: 26 |
| T3D3507 | Capecitabine 154361-50-9 | C15H22FN3O6 359.350 g/mol |  |
| Capecitabine is a prodrug that is selectively tumour-activated to its cytotoxic moiety, fluorouracil, by thymidine phosphorylase. Fluorouracil is further metabolized t...more Number of Targets: 4 |
| T3D3868 | Isoxaflutole 141112-29-0 | C15H12F3NO4S 359.320 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D1475 | Zinc ammonium sulfate 7783-24-6 | H8N2O8S2Zn2 359.020 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D4710 | Prednisone 53-03-2 | C21H26O5 358.428 g/mol |  |
| Prednisone is a glucocorticoid receptor agonist. It is first metabolized in the liver to its active form, prednisolone. Prednisolone crosses cell membranes and binds w...more Number of Targets: 4 |
| T3D2753 | Indomethacin 53-86-1 | C19H16ClNO4 357.788 g/mol |  |
| Antiinflammatory effects of Indomethacin are believed to be due to inhibition of cylooxygenase in platelets which leads to the blockage of prostaglandin synthesis. Ant...more Number of Targets: 29 |
| T3D3809 | Chlorsulfuron 64902-72-3 | C12H12ClN5O4S 357.773 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D3056 | Cinolazepam 75696-02-5 | C18H13ClFN3O2 357.766 g/mol |  |
| Cinolazepam binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitte...more Number of Targets: 18 |
| T3D2911 | Nalbuphine 20594-83-6 | C21H27NO4 357.443 g/mol |  |
| Receptor studies show that nalbuphine exerts its action via binding to mu, kappa, and delta receptors, but not to sigma receptors. Nalbuphine is primarily a kappa agon...more Number of Targets: 3 |
| T3D3818 | Cyhalofop-butyl 122008-85-9 | C20H20FNO4 357.376 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 4 |
| T3D2957 | Balsalazide 80573-04-2 | C17H15N3O6 357.318 g/mol |  |
| The mechanism of action of 5-aminosalicylic acid is unknown, but appears exert its anti-inflammatory effects locally (in the GI tract) rather than systemically. Mucosa...more Number of Targets: 4 |
| T3D3068 | Silver sulfadiazine 22199-08-2 | C10H9AgN4O2S 357.137 g/mol |  |
| Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemical techniques have revealed that the mechanism of action of silver sulf...more Number of Targets: 1 |
| T3D4981 | Pioglitazone 111025-46-8 | C19H20N2O3S 356.439 g/mol |  |
| Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and...more Number of Targets: 3 |
| T3D2105 | 1,2,3,6,7-Pentachlorodibenzo-p-dioxin 71925-15-0 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2104 | 1,2,4,6,8-Pentachlorodibenzo-p-dioxin 71998-76-0 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2103 | 1,2,4,7,9-Pentachlorodibenzo-p-dioxin 82291-37-0 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2102 | 1,2,3,4,6-Pentachlorodibenzo-p-dioxin 67028-19-7 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2101 | 1,2,3,6,8-Pentachlorodibenzo-p-dioxin 71925-16-1 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2100 | 1,2,3,6,9-Pentachlorodibenzo-p-dioxin 82291-34-7 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2099 | 1,2,3,7,9-Pentachlorodibenzo-p-dioxin 71925-17-2 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |