Browsing Toxins By Category
Displaying toxin 2451 - 2475 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0637 | Bisphenol A 1980-05-07 | C15H16O2 228.286 g/mol |  |
| Bisphenol is an endocrine disruptor. Low doses of bisphenol A can mimic the body's own hormones, possibly causing negative health effects. There is thus concern that l...more Number of Targets: 43 |
| T3D0932 | Biscarbofuran N,N'-disulfide 39995-74-9 | C24H28N2O6S2 504.619 g/mol |  |
| Biscarbofuran N,N'-disulfide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation o...more Number of Targets: 2 |
| T3D1249 | Bis(tributyltin) oxide 56-35-9 | C24H54OSn2 596.100 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 8 |
| T3D1565 | Bis(isobutyl)aluminum chloride 1779-25-5 | C8H18AlCl 176.663 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0683 | Bis(cyclooctadiene)nickel(0) 1295-35-8 | C16H24Ni 275.055 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D1427 | Bis(benzene)chromium 1271-54-1 | C12H12Cr 208.223 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1404 | Bis(3-fluorosalicylaldehyde)-ethylenediimine-cobalt 62207-76-5 | C16H12CoF2N2O2 361.209 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D0194 | Bis(2-methoxyethyl) phthalate 34006-76-3 | C13H16O4 236.264 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D0088 | Bis(2-chloroethyl) ether 111-44-4 | C4H8Cl2O 143.012 g/mol |  |
| BCEE is extremely meabolized, with thiodiglycolic acid (TDGA) being the principal endproduct. The pathway leading to TDGA formation is uncertain, but probably involves...more Number of Targets: 38 |
| T3D1584 | Bis(2,4-pentanedionato) palladium(II) 14024-61-4 | C10H14O4Pd 304.640 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1583 | Bis(1,5-diphenyl-1,4-pentadien-3-one) palladium(0) 32005-36-0 | C34H30O2Pd 577.020 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D0389 | Biphenyl 92-52-4 | C12H10 154.208 g/mol |  |
| Biphenyl alters the permeability properties of mitochondrial membranes (A279). Number of Targets: 5 |
| T3D2897 | Biperiden 514-65-8 | C21H29NO 311.461 g/mol |  |
| Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of...more Number of Targets: 5 |
| T3D2690 | Biotin 58-85-5 | C10H16N2O3S 244.311 g/mol |  |
| Biotin is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, includ...more Number of Targets: 10 |
| T3D1844 | Bioresmethrin 28434-01-7 | C22H26O3 338.440 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 19 |
| T3D4886 | Biochanin A 491-80-5 | C16H12O5 284.264 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D4350 | Bilirubin 635-65-4 | C33H36N4O6 584.662 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2596 | Bifunctional hemolysin/adenylate cyclase (Bordetella pertussis) 566070-83-5 | Not Available 177519.955 g/mol |  |
| After binding of the pertussis AC toxin to the cell, binding to calcium ions leads to the translocation of its adenylate cyclase domain into the cytoplasm, where, upon...more Number of Targets: 1 |
| T3D1843 | Bifenthrin 82657-04-3 | C23H22ClF3O2 422.868 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 33 |
| T3D3798 | Bifenazate 149877-41-8 | C17H20N2O3 300.352 g/mol |  |
| Not Available Number of Targets: 17 |
| T3D4073 | Bicuculline 485-49-4 | C20H17NO6 367.352 g/mol |  |
| The action of bicuculline is primarily on the ionotropic GABAA receptors, which are ligand-gated ion channels concerned chiefly with the passing of chloride ions acros...more Number of Targets: 4 |
| T3D4818 | Bicalutamide 90357-06-5 | C18H14F4N2O4S 430.373 g/mol |  |
| Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin which stimula...more Number of Targets: 5 |
| T3D2958 | Bethanechol 674-38-4 | C7H17N2O2 161.222 g/mol |  |
| Bethanechol directly stimulates cholinergic receptors in the parasympathetic nervous system while stimulating the ganglia to a lesser extent. Its effects are predomina...more Number of Targets: 4 |
| T3D4053 | beta-Zearalenol 71030-11-0 | C18H24O5 320.380 g/mol |  |
| Mycotoxins, such as alpha-zearalenol (alpha-ZOL) and beta-zearalenol (beta-ZOL), as contaminants of animal food can impair fertility and can cause abnormal fetal devel...more Number of Targets: 1 |
| T3D2491 | beta-Pompilidotoxin 216064-36-7 | Not Available 1558.860 g/mol |  |
| Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more Number of Targets: 10 |