Browsing Toxins By Category
Displaying toxin 2151 - 2175 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3814 | Clorophene 120-32-1 | C13H11ClO 218.679 g/mol |  |
| AR binding was observed for clorophene, which were both associated with delays in sexual development and decrements in reproductive performance. Number of Targets: 17 |
| T3D2842 | Clorazepate 23887-31-2 | C16H11ClN2O3 314.723 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D3813 | Clopyralid-olamine 57754-85-5 | C8H10Cl2N2O3 253.083 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D4488 | Clopyralid 1702-17-6 | C6H3Cl2NO2 192.000 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D3812 | Cloprop 101-10-0 | C9H9ClO3 200.619 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D2829 | Clonidine 4205-90-7 | C9H9Cl2N3 230.094 g/mol |  |
| Clonidine acts as an agonist at presynaptic alpha(2)-receptors in the nucleus tractus solitarius of the medulla oblongata. Stimulation of these receptors results in th...more Number of Targets: 7 |
| T3D2973 | Clonazepam 1622-61-3 | C15H10ClN3O3 315.711 g/mol |  |
| Allosteric interactions between central benzodiazepine receptors and gamma-aminobutyric acid (GABA) receptors potentiate the effects of GABA. As GABA is an inhibitory ...more Number of Targets: 21 |
| T3D3032 | Clomipramine 303-49-1 | C19H23ClN2 314.852 g/mol |  |
| Clomipramine is a strong, but not completely selective serotonin reuptake inhibitor (SRI), as the active main metabolite desmethyclomipramine acts preferably as an inh...more Number of Targets: 16 |
| T3D4976 | Clomifene 911-45-5 | C26H28ClNO 405.960 g/mol |  |
| Clomifene has both estrogenic and anti-estrogenic properties, but its precise mechanism of action has not been determined. Clomifene appears to stumulate the release o...more Number of Targets: 2 |
| T3D4487 | Clomazone 81777-89-1 | C12H14ClNO2 239.698 g/mol |  |
| Clomazone induces oxidative stress and AChE inhibition in human erythrocytes (in vitro), suggesting a role for reactive oxygen species in the toxicity mechanism induce...more Number of Targets: 8 |
| T3D4784 | Clofibrate 637-07-0 | C12H15ClO3 242.699 g/mol |  |
| Clofibrate increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. Chylomicrons are degraded, VLDLs are ...more Number of Targets: 2 |
| T3D3811 | Clofentezine 74115-24-5 | C14H8Cl2N4 303.146 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D0012 | Clofenotane 50-29-3 | C14H9Cl5 354.486 g/mol |  |
| DDT toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDT reduces potassium transport across the membrane. DDT inhibits the inacti...more Number of Targets: 64 |
| T3D0950 | Cloethocarb 51487-69-5 | C11H14ClNO4 259.686 g/mol |  |
| Cloethocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D2663 | Clodronate 10596-23-3 | CH4Cl2O6P2 244.892 g/mol |  |
| The bisphosphonate group binds strongly to the bone mineral, hydroxyapatite. This explains the specific pharmacological action of these compounds on mineralized tissue...more Number of Targets: 9 |
| T3D4486 | Clodinafop-propargyl 105512-06-9 | C17H13ClFNO4 349.741 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D4564 | Clobazam 22316-47-8 | C16H13ClN2O2 300.740 g/mol |  |
| Clobazam binds at distinct binding sites associated with the chloride ionopore at the post-synaptic GABA receptor. These GABA receptors are in various locations in the...more Number of Targets: 18 |
| T3D3497 | Clindamycin 18323-44-9 | C18H33ClN2O5S 424.983 g/mol |  |
| Systemic/vaginal clindamycin inhibits protein synthesis of bacteria by binding to the 50S ribosomal subunits of the bacteria. Specifically, it binds primarily to the 2...more Number of Targets: 0 |
| T3D4774 | Cladribine 4291-63-8 | C10H12ClN5O3 285.687 g/mol |  |
| Cladribine is structurally related to fludarabine and pentostatin but has a different mechanism of action. Although the exact mechanism of action has not been fully de...more Number of Targets: 14 |
| T3D4295 | Citrulline 372-75-8 | C6H13N3O3 175.186 g/mol |  |
| L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn responsible for citrulline's therapeutic affects. Many of L-arginine's act...more Number of Targets: 13 |
| T3D3597 | Citrinin 518-75-2 | C13H14O5 250.247 g/mol |  |
| Citrinin produces proximal tubular necrosis, but only after transport into proximal tubular cells. It utilizes the organic anion transporter for entry into the cells, ...more Number of Targets: 28 |
| T3D3737 | Citreoviridin A 25425-12-1 | C23H30O6 402.481 g/mol |  |
| Citreoviridin inhibits both membrane-bound and soluble mitochondrial ATPases. In particular, it inhibits synaptosomal Na+/K+-ATPase, altering synaptic transmission, an...more Number of Targets: 15 |
| T3D2715 | Citalopram 59729-33-8 | C20H21FN2O 324.392 g/mol |  |
| The antidepressant, antiobsessive-compulsive, and antibulimic actions of citalopram are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. Ci...more Number of Targets: 14 |
| T3D4686 | Cisplatin 15663-27-1 | Cl2H4N2Pt 298.035 g/mol |  |
| Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases, resulting in the DNA being fragmented by repair enzymes in their atte...more Number of Targets: 1 |
| T3D1025 | Cismethrin 35764-59-1 | C22H26O3 338.440 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 19 |