Browsing Toxins By Category
Displaying toxin 1826 - 1850 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2636 | Disintegrin echistatin (Echis carinatus) Not Available | Not Available 5424.090 g/mol |  |
| Disintegrins work by countering blood clotting steps, inhibiting the clumping of platelets. They inhibit fibrinogen interaction with platelet receptors expressed on gl...more Number of Targets: 2 |
| T3D4498 | Diquat dibromide 85-00-7 | C12H12Br2N2 344.045 g/mol |  |
| Not Available Number of Targets: 17 |
| T3D0963 | Dipropylcarbamothioic acid S-ethyl ester 759-94-4 | C9H19NOS 189.318 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 7 |
| T3D3121 | Diphtheria toxin (Corynephage omega) Not Available | Not Available 60814.155 g/mol |  |
| Diphtheria toxin consists of a single polypeptide. Proteolysis yields two fragments (A and B) which are held together by a disulfide bond. The toxin binds to EGF-like ...more Number of Targets: 1 |
| T3D1308 | Diphenylcyanoarsine 23525-22-6 | C13H10AsN 255.147 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 46 |
| T3D1307 | Diphenylchlorarsine 712-48-1 | C12H10AsCl 264.582 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 46 |
| T3D4497 | Diphenylamine 122-39-4 | C12H11N 169.222 g/mol |  |
| Diphenylamine uncouples mitochondrial oxidative phosphorylation, resulting in a decrease in hepatocellular ATP content and consequently hepatocyte injury (A15350). Sho...more Number of Targets: 7 |
| T3D1818 | Diphenyl diselenide 1666-13-3 | C12H10Se2 312.130 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D2978 | Diphenoxylate 915-30-0 | C30H32N2O2 452.587 g/mol |  |
| Diphenoxylate is an opiate receptor agonists that stimulate mu receptors in GI to decrease the peristalsis and constrict the sphincters. Diphenoxylate has a direct eff...more Number of Targets: 3 |
| T3D2976 | Diphenhydramine 58-73-1 | C17H21NO 255.355 g/mol |  |
| Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the...more Number of Targets: 8 |
| T3D1870 | Dioxygenyl hexafluoroantimonate 12361-66-9 | F6O2Sb 267.750 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D0962 | Dioxacarb 6988-21-2 | C11H13NO4 223.225 g/mol |  |
| Dioxacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D4030 | Dinophysistoxin 1 81720-10-7 | C45H70O13 819.030 g/mol |  |
| Dinophysistoxin 1 (DTX1) is the analogue of okadaic acid causing diarrheic shellfish poisoning (DSP) in humans shortly after the ingestion of contaminated seafood. DTX...more Number of Targets: 0 |
| T3D3559 | Dinitrogen tetroxide 10544-72-6 | N2O4 92.011 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D4496 | Diniconazole 83657-24-3 | C15H17Cl2N3O 326.221 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D0961 | Dimetilan 644-64-4 | C10H16N4O3 240.259 g/mol |  |
| Dimetilan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D0749 | Dimethylzinc 544-97-8 | C2H6Zn 95.478 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1239 | Dimethyltin dichloride 753-73-1 | C2H6Cl2Sn 219.690 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1281 | Dimethyltin bis(isooctyl mercaptoacetate) 26636-01-1 | C22H44O4S2Sn 555.420 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D4841 | Dimethylethanolamine 108-01-0 | C4H11NO 89.136 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0304 | Dimethylarsine 593-57-7 | C2H7As 105.999 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0075 | Dimethylarsinate 15132-04-4 | C2H7AsO2 137.997 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through different mechanisms. At the level of the citric acid cycle, arsenic inhibits the pyruvate dehydrogenase and...more Number of Targets: 54 |
| T3D4148 | Dimethylamine 124-40-3 | C2H7N 45.084 g/mol |  |
| Uremic toxins such as dimethylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can sti...more Number of Targets: 5 |
| T3D2982 | Dimethyl sulfoxide 67-68-5 | C2H6OS 78.133 g/mol |  |
| The mechanism of dimethyl sulfoxide's actions is not well understood. Dimethyl sulfoxide has demonstrated antioxidant activity in certain biological settings. For exam...more Number of Targets: 14 |
| T3D3652 | Dimethyl phthalate 131-11-3 | C10H10O4 194.184 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 8 |