Browsing Toxins By Category
Displaying toxin 1776 - 1800 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3587 | epsilon-Amanitin 21705-02-2 | C39H53N9O14S 903.955 g/mol |  |
| The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more Number of Targets: 14 |
| T3D2791 | Epirubicin 56420-45-2 | C27H29NO11 543.519 g/mol |  |
| Epirubicin has antimitotic and cytotoxic activity. It inhibits nucleic acid (DNA and RNA) and protein synthesis through a number of proposed mechanisms of action: Epir...more Number of Targets: 3 |
| T3D2530 | Epibatidine 140111-52-0 | C11H13ClN2 208.687 g/mol |  |
| Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074) Number of Targets: 17 |
| T3D3040 | Ephedrine 299-42-3 | C10H15NO 165.232 g/mol |  |
| Ephedrine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 4 |
| T3D2619 | Enterotoxin type B Not Available | Not Available 31435.675 g/mol |  |
| The action of enterotoxins leads to increased chloride ion permeability of the apical membrane of intestinal mucosal cells. These membrane pores are activated by eithe...more Number of Targets: 0 |
| T3D2618 | Enterotoxin type A Not Available | Not Available 29669.310 g/mol |  |
| The action of enterotoxins leads to increased chloride ion permeability of the apical membrane of intestinal mucosal cells. These membrane pores are activated by eithe...more Number of Targets: 0 |
| T3D3967 | Enterolactone 76543-15-2 | C18H18O4 298.333 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D2808 | Entacapone 130929-57-6 | C14H15N3O5 305.286 g/mol |  |
| The mechanism of action of entacapone is believed to be through its ability to inhibit COMT in peripheral tissues, altering the plasma pharmacokinetics of levodopa. Wh...more Number of Targets: 1 |
| T3D3759 | Enniatin B1 19914-20-6 | C34H59N3O9 653.847 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3758 | Enniatin B 917-13-5 | C33H57N3O9 639.820 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3757 | Enniatin A1 4530-21-6 | C35H61N3O9 667.874 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3756 | Enniatin A 2503-13-1 | C36H63N3O9 681.900 g/mol |  |
| Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more Number of Targets: 5 |
| T3D3860 | Enilconazole 35554-44-0 | C14H14Cl2N2O 297.180 g/mol |  |
| Not Available Number of Targets: 36 |
| T3D2717 | Enflurane 13838-16-9 | C3H2ClF5O 184.492 g/mol |  |
| Enflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Enflurane a...more Number of Targets: 12 |
| T3D0063 | Endrin ketone 53494-70-5 | C12H8Cl6O 380.909 g/mol |  |
| Endrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more Number of Targets: 38 |
| T3D0069 | Endrin aldehyde 7421-93-4 | C12H8Cl6O 380.909 g/mol |  |
| Endrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more Number of Targets: 38 |
| T3D0041 | Endrin 72-20-8 | C12H8Cl6O 380.909 g/mol |  |
| Endrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more Number of Targets: 42 |
| T3D0055 | Endosulfan sulfate 1031-07-8 | C9H6Cl6O4S 422.925 g/mol |  |
| Endosulfan sulfate antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced ...more Number of Targets: 42 |
| T3D4738 | Encainide 66778-36-7 | C22H28N2O2 352.470 g/mol |  |
| Encainide is a sodium channel blocker, binding to voltage gated sodium channels. It stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the in...more Number of Targets: 1 |
| T3D3755 | Emodin 518-82-1 | C15H10O5 270.237 g/mol |  |
| Emodin is moderately cytotoxic and can inhibit the growth of many cell types by interfering with the cell cycle, possibly by stimulating the expression of p53 and p21....more Number of Targets: 20 |
| T3D3754 | Emestrin 97816-62-1 | C27H22N2O10S2 598.601 g/mol |  |
| Emestrin causes degeneration of the mitochondria in both cardiac muscle cells and hepatocytes, leading to necrosis. It is also known to act as an antagonist at the che...more Number of Targets: 2 |
| T3D3831 | Emamectin benzoate 155569-91-8 | C56H81NO15 1008.240 g/mol |  |
| Not Available Number of Targets: 40 |
| T3D1044 | Emamectin B1b 121424-52-0 | C48H73NO13 872.092 g/mol |  |
| It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more Number of Targets: 11 |
| T3D1043 | Emamectin B1a 121124-29-6 | C49H75NO13 886.119 g/mol |  |
| It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more Number of Targets: 11 |
| T3D3694 | Elymoclavine 548-43-6 | C16H18N2O 254.327 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 6 |