Browsing Toxins By Category
Displaying toxin 1501 - 1525 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0084 | Hydrazine 302-01-2 | H4N2 32.045 g/mol |  |
| At least two mechanisms of action have been observed. One involves the direct binding of those hydrazines with a free amino group (hydrazine and 1,1-dimethylhydrazine)...more Number of Targets: 0 |
| T3D2646 | Hydralysin (Chlorohydra viridissima) Not Available | Not Available 26212.075 g/mol |  |
| Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170) Number of Targets: 0 |
| T3D2499 | Huwentoxin 526224-73-7 | Not Available 9318.830 g/mol |  |
| Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more Number of Targets: 17 |
| T3D3673 | HT-2 Toxin 26934-87-2 | C22H32O8 424.485 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3858 | HPTE 2971-36-0 | C14H11Cl3O2 317.595 g/mol |  |
| 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane (HPTE), acts as an estrogen analogue. HPTE is an estrogen receptor alpha agonist, and also acts as an antagonist at the...more Number of Targets: 29 |
| T3D2581 | Hongotoxin 203526-59-4 | Not Available 4226.080 g/mol |  |
| Hongotoxin inhibits voltage-gated potassium channels. (L1049) Number of Targets: 4 |
| T3D4287 | Homogentisic acid 451-13-8 | C8H8O4 168.147 g/mol |  |
| Extremely high levels of homogentisic acid are found in patients with the inborn error of metabolism (IEM) called Alkaptonuria. Homogentisic acid spontaneously undergo...more Number of Targets: 0 |
| T3D4161 | Homocysteine 454-29-5 | C4H9NO2S 135.185 g/mol |  |
| Nitrosylation converts homocysteine (Hcy) into a methionine analogue, S-nitroso-Homocysteine, which can substitute for methionine in protein synthesis in biological sy...more Number of Targets: 5 |
| T3D2492 | Holocyclotoxin 88254-04-0 | Not Available 7834.125 g/mol |  |
| Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834) Number of Targets: 0 |
| T3D2528 | Histrionicotoxin 34272-51-0 | C19H25NO 283.408 g/mol |  |
| Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1072) Number of Targets: 16 |
| T3D4159 | Hippuric acid 495-69-2 | C9H9NO3 179.173 g/mol |  |
| Uremic toxins such as hippuric acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can sti...more Number of Targets: 4 |
| T3D4515 | Hexythiazox 78587-05-0 | C17H21ClN2O2S 352.879 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D4855 | Hexylresorcinol 136-77-6 | C12H18O2 194.270 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D3039 | Hexobarbital 56-29-1 | C12H16N2O3 236.267 g/mol |  |
| Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A receptor, increasing the duration of time for which the Cl- ionopore is open...more Number of Targets: 11 |
| T3D4740 | Hexestrol 84-16-2 | C18H22O2 270.366 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D3857 | Hexazinone 51235-04-2 | C12H20N4O2 252.313 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0018 | Hexavalent chromium 18540-29-9 | Cr 51.996 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D2403 | Hexane 110-54-3 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 6 |
| T3D4181 | Hexanal 66-25-1 | C6H12O 100.159 g/mol |  |
| Uremic toxins such as hexanal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate...more Number of Targets: 4 |
| T3D0676 | Hexamminecobalt(III) chloride 10534-89-1 | Cl3CoH18N6 267.475 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1661 | Hexamethylene diisocyanate 822-06-0 | C8H12N2O2 168.193 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 40 |
| T3D1286 | Hexakis(2-methyl-2-phenylpropyl)distannoxane 13356-08-6 | C60H80OSn2 1054.700 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1872 | Hexafluoroantimonic acid 16950-06-4 | F6HSb 236.760 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D4286 | Hexacosanoic acid 506-46-7 | C26H52O2 396.690 g/mol |  |
| Adrenoleukodystrophy (ALD) is caused by mutations in ABCD1, a gene located on the X chromosome that codes for ALD, a peroxisomal membrane transporter protein. The exac...more Number of Targets: 0 |
| T3D4514 | Hexaconazole 79983-71-4 | C14H17Cl2N3O 314.210 g/mol |  |
| Not Available Number of Targets: 13 |