Browsing Toxins By Category
Displaying toxin 1401 - 1425 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1856 | Jasmolin II 1172-63-0 | C22H30O5 374.471 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D1855 | Jasmolin I 4466-14-2 | C21H30O3 330.461 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D3766 | Janthitrem G 90986-51-9 | C39H51NO6 629.825 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3765 | Janthitrem F 90986-52-0 | C39H51NO7 645.825 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3764 | Janthitrem E 90986-50-8 | C37H49NO6 603.788 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3763 | Janthitrem C 73561-91-8 | C37H47NO4 569.773 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3762 | Janthitrem B 73561-90-7 | C37H47NO5 585.773 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3516 | Itraconazole 84625-61-6 | C35H38Cl2N8O4 705.633 g/mol |  |
| Itraconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the f...more Number of Targets: 6 |
| T3D3868 | Isoxaflutole 141112-29-0 | C15H12F3NO4S 359.320 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D3867 | Isoxaben 82558-50-7 | C18H24N2O4 332.394 g/mol |  |
| Not Available Number of Targets: 20 |
| T3D3468 | Isopropylbenzene 98-82-8 | C9H12 120.192 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D4699 | Isopropyl alcohol 67-63-0 | C3H8O 60.095 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D4979 | Isoprenaline 7683-59-2 | C11H17NO3 211.258 g/mol |  |
| The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzy...more Number of Targets: 7 |
| T3D0843 | Isopimpinellin 482-27-9 | C13H10O5 246.216 g/mol |  |
| Isopimpinelin strongly inhibits insulin-stimulated lipogenesis. It induces hepatic GSTs and is potent inhibitor of cytochrome P450 1A1/1B1. Oral administration of isop...more Number of Targets: 3 |
| T3D1662 | Isophorone diisocyanate 4098-71-9 | C12H18N2O2 222.284 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 42 |
| T3D4851 | Isopentyl acetate 123-92-2 | C7H14O2 130.185 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D3429 | Isopentane 78-78-4 | C5H12 72.149 g/mol |  |
| Pentane is a central nervous system depressant. It affects the peripheral nervous system through demyelinization and axonal degeneration. (T29) Number of Targets: 0 |
| T3D4777 | Isoniazid 54-85-3 | C6H7N3O 137.139 g/mol |  |
| Isoniazid is a prodrug and must be activated by bacterial catalase. Specficially, activation is associated with reduction of the mycobacterial ferric KatG catalase-per...more Number of Targets: 3 |
| T3D0976 | Isolan 119-38-0 | C10H17N3O2 211.261 g/mol |  |
| Isolan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of ...more Number of Targets: 2 |
| T3D0831 | Isoimperatorin 482-45-1 | C16H14O4 270.280 g/mol |  |
| Isoimperatorin is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 4 |
| T3D2882 | Isoflurane 26675-46-7 | C3H2ClF5O 184.492 g/mol |  |
| Isoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Isoflurane...more Number of Targets: 9 |
| T3D4880 | Isoeugenol 97-54-1 | C10H12O2 164.201 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D1023 | Isodrin 465-73-6 | C12H8Cl6 364.910 g/mol |  |
| It antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chlori...more Number of Targets: 38 |
| T3D0777 | Isocyanic acid 75-13-8 | CHNO 43.025 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D3033 | Isocarboxazid 59-63-2 | C12H13N3O2 231.251 g/mol |  |
| Isocarboxazid works by irreversibly blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system. MAO subtypes A and B are involv...more Number of Targets: 2 |