Browsing Toxins By Category
Displaying toxin 1251 - 1275 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3872 | Mancozeb 8018-01-07 | C8H12MnN4S8Zn 541.075 g/mol |  |
| Not Available Number of Targets: 82 |
| T3D1704 | Malononitrile 109-77-3 | C3H2N2 66.061 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4182 | Malondialdehyde 542-78-9 | C3H4O2 72.063 g/mol |  |
| Uremic toxins such as malondialdehyde are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can s...more Number of Targets: 5 |
| T3D3871 | Maleic hydrazide 123-33-1 | C4H4N2O2 112.087 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4800 | Maleic acid 110-16-7 | C4H4O4 116.072 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D3870 | Malathion 121-75-5 | C10H19O6PS2 330.358 g/mol |  |
| Malathion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 16 |
| T3D4519 | Malaoxon 1634-78-2 | C10H19O7PS 314.292 g/mol |  |
| Malaoxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 9 |
| T3D2587 | Maitotoxin 59392-53-9 | C164H256Na2O68S2 3425.856 g/mol |  |
| Maitotoxin activates calcium permeable, non-selective cation channels, leading to an increase in levels of cytosolic calcium ions. It is thought that maitotoxin leads ...more Number of Targets: 0 |
| T3D2851 | Magnesium Sulfate 7487-88-9 | MgO4S 120.368 g/mol |  |
| Magnesium is the second most plentiful cation of the intracellular fluids. It is essential for the activity of many enzyme systems and plays an important role with reg...more Number of Targets: 6 |
| T3D1912 | Magnesium perchlorate 10034-81-8 | Cl2MgO8 223.206 g/mol |  |
| The primary and most sensitive target of the perchlorate anion (perchlorate) is the thyroid gland. Perchlorate inhibits the transport of iodide (I-) from the blood int...more Number of Targets: 4 |
| T3D3567 | Magnesium nitrate 10377-60-3 | MgN2O6 148.315 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D1739 | Magnesium bromide 7789-48-2 | Br2Mg 184.113 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0293 | Magnesium arsenate 10103-50-1 | As2Mg3O8 350.753 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 |
| T3D1541 | Magnesium aluminate 12068-51-8 | Al2MgO4 142.266 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1874 | Magic acid (fluorosulfuric acid-antimony pentafluoride) 23854-38-8 | F6HO3SSb 316.820 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1809 | m-Xylyl bromide 620-13-3 | C8H9Br 185.061 g/mol |  |
| Organobromide compounds such as m-Xylyl bromide are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of ...more Number of Targets: 1 |
| T3D0058 | m-Xylene 108-38-3 | C8H10 106.165 g/mol |  |
| m-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 5 |
| T3D4992 | m-Dichlorobenzene 541-73-1 | C6H4Cl2 147.002 g/mol |  |
| The liver damage caused in rats by 1,3-dichlorobenzene is accompanied by induction of xenobiotic metabolizing enzymes of the phenobarbital type. In rats, a disturbance...more Number of Targets: 0 |
| T3D0979 | m-Cumenyl methylcarbamate 64-00-6 | C11H15NO2 193.242 g/mol |  |
| m-Cumenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of t...more Number of Targets: 2 |
| T3D1842 | m-Cresol 108-39-4 | C7H8O 108.138 g/mol |  |
| m-Cresol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 5 |
| T3D3695 | Lysergol 602-85-7 | C16H18N2O 254.327 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 10 |
| T3D3687 | Lysergic acid hydroxyethylamide 3343-15-5 | C18H21N3O2 311.378 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 9 |
| T3D3582 | Lysergic Acid Diethylamide 50-37-3 | C20H25N3O 323.432 g/mol |  |
| LSD preferentially inhibits serotonergic cell firing by acting as an agonist at the 5-HT1A receptors in the raphe nuclei, locus coeruleus, and cortex. It also acts as ...more Number of Targets: 17 |
| T3D4088 | Lyngbyatoxin A 70497-14-2 | C27H39N3O2 437.618 g/mol |  |
| Lyngbyatoxin A is a tumor promoter. Lyngbyatoxin A and related compounds bind to the cysteine-rich C1 domains (C1A and C1B) of protein kinase C (PKC) isozymes to activ...more Number of Targets: 2 |
| T3D3952 | Lymecycline 992-21-2 | C29H38N4O10 602.633 g/mol |  |
| Tetracyclines target the 28S small subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result tetracyclines are cytotoxic ...more Number of Targets: 1 |