Browsing Toxins By Category
Displaying toxin 1101 - 1125 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4748 | Methyltestosterone 58-18-4 | C20H30O2 302.451 g/mol |  |
| The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by co...more Number of Targets: 4 |
| T3D2786 | Methylphenidate 113-45-1 | C14H19NO2 233.306 g/mol |  |
| Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal...more Number of Targets: 3 |
| T3D3977 | Methylparaben 99-76-3 | C8H8O3 152.147 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D0123 | Methylmercury 22967-92-6 | CH3Hg 215.620 g/mol |  |
| Methylmercury is neurotoxic. It potently affects the release of neurotransmitter from presynaptic nerve terminals. Methylmercury alters calcium ion concentrations by a...more Number of Targets: 70 |
| T3D1350 | Methylmercuric dicyanamide 502-39-6 | C3H6HgN4 298.700 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 88 |
| T3D0360 | Methylmercuric chloride 125-09-3 | CH3ClHg 251.080 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D4404 | Methylmalonic acid 516-05-2 | C4H6O4 118.088 g/mol |  |
| Methylmalonic acid is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This me...more Number of Targets: 0 |
| T3D4170 | Methylguanidine 471-29-4 | C2H7N3 73.097 g/mol |  |
| Uremic toxins such as methylguanidine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can s...more Number of Targets: 3 |
| T3D4876 | Methyleugenol 93-15-2 | C11H14O2 178.228 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3686 | Methylergonovine 113-42-8 | C20H25N3O2 339.431 g/mol |  |
| Ergoline alkaloids have been shown to have the significant affinity towards the 5-HT1 and 5-HT2 serotonin receptors, D1 and D2 dopamine receptors, and alpha-adrenergic...more Number of Targets: 4 |
| T3D1676 | Methylene thiocyanate 6317-18-6 | C3H2N2S2 130.191 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 66 |
| T3D1664 | Methylene diphenyl diisocyanate 101-68-8 | C15H10N2O2 250.252 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D1673 | Methylene bis(4-cyclohexylisocyanate) 5124-30-1 | C15H22N2O2 262.347 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D3577 | Methyldopa 555-30-6 | C10H13NO4 211.215 g/mol |  |
| Although the mechanism of action has yet to be conclusively demonstrated, the resultant hypotensive effect is most likely due to the drug's action on the CNS. Methyldo...more Number of Targets: 4 |
| T3D1311 | Methyldichloroarsine 593-89-5 | CH3AsCl2 160.862 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 |
| T3D3466 | Methylcyclopentane 96-37-7 | C6H12 84.160 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D1138 | Methylcyclopentadienyl manganese tricarbonyl 12108-13-3 | C9H7MnO3 218.088 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D0679 | Methylcobalamin 13422-55-4 | C63H91CoN13O14P 1344.382 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D0806 | Methylchlorophenoxypropionic acid 93-65-2 | C10H11ClO3 214.646 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 3 |
| T3D0309 | Methylarsonic acid, monosodium salt 2163-80-6 | CH4AsNaO3 161.952 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0308 | Methylarsonic acid, disodium salt 19444-53-2 | CH5AsNa2O3 185.949 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0303 | Methylarsine 593-52-2 | CH5As 91.972 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D3570 | Methylammonium nitrate 22113-87-7 | CH6N2O3 94.070 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D4151 | Methylamine 74-89-5 | CH5N 31.057 g/mol |  |
| Uremic toxins such as methylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimu...more Number of Targets: 3 |
| T3D1525 | Methylaluminoxane 120144-90-3 | C3H9AlO 88.085 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |