Browsing Toxins By Category
Displaying toxin 601 - 625 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4535 | Rimsulfuron 122931-48-0 | C14H17N5O7S2 431.444 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D2875 | Riluzole 1744-22-5 | C8H5F3N2OS 234.198 g/mol |  |
| The mode of action of riluzole is unknown. Its pharmacological properties include the following, some of which may be related to its effect: 1) an inhibitory effect on...more Number of Targets: 5 |
| T3D3018 | Rifapentine 61379-65-5 | C47H64N4O12 877.031 g/mol |  |
| Rifapentine has shown higher bacteriostatic and bactericidal activities especially against intracellular bacteria growing in human monocyte-derived macrophages. Rifape...more Number of Targets: 0 |
| T3D2969 | Rifampin 13292-46-1 | C43H58N4O12 822.940 g/mol |  |
| Rifampin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA synthesis and cell death. Number of Targets: 10 |
| T3D2838 | Rifabutin 72559-06-9 | C46H62N4O11 847.005 g/mol |  |
| Rifabutin acts via the inhibition of DNA-dependent RNA polymerase in gram-positive and some gram-negative bacteria, leading to a suppression of RNA synthesis and cell ...more Number of Targets: 2 |
| T3D3021 | Ridogrel 110140-89-1 | C18H17F3N2O3 366.334 g/mol |  |
| Ridogrel inhibits thromboxane A2 synthase and also blocks the thromboxane A2/prostaglandin endoperoxide receptors.
Thromboxane synthetase produces thromboxane in plate...more Number of Targets: 3 |
| T3D2481 | Ricin 9009-86-3 | Not Available 64089.975 g/mol |  |
| Pure ricin consists of a neutral A chain and an acidic B chain connected by S--S bonds. The A chain is capable of inhibiting protein synthesis which results in its tox...more Number of Targets: 1 |
| T3D4817 | Riboflavin 83-88-5 | C17H20N4O6 376.364 g/mol |  |
| Binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and f...more Number of Targets: 4 |
| T3D4793 | Rhodamine 6g 989-38-8 | C28H31N2O3 443.557 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D4060 | Retronecine 480-85-3 | C8H13NO2 155.194 g/mol |  |
| Retronecine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic...more Number of Targets: 0 |
| T3D4910 | Retinol acetate 127-47-9 | C22H32O2 328.488 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D3771 | Restrictocin (Aspergillus restrictus) 1406-72-0 | Not Available 19595.005 g/mol |  |
| Restrictocin is a highly specific ribotoxin that inhibits protein synthesis by cleaving a single phosphodiester bond in the sarcin/ricin loop (SRL) of the 23S−28S rRNA...more Number of Targets: 1 |
| T3D1027 | Resmethrin 10453-86-8 | C22H26O3 338.440 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 30 |
| T3D3084 | Resiniferatoxin 57444-62-9 | C37H40O9 628.708 g/mol |  |
| Resiniferatoxin activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission of physiological pain...more Number of Targets: 1 |
| T3D2713 | Reserpine 50-55-5 | C33H40N2O9 608.679 g/mol |  |
| Reserpine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the p...more Number of Targets: 18 |
| T3D2720 | Reboxetine 98769-81-4 | C19H23NO3 313.391 g/mol |  |
| Reboxetine is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake in vitro to a similar extent to the tricyclic antidepressant desmethy...more Number of Targets: 1 |
| T3D4063 | Ranunculin 644-69-9 | C11H16O8 276.240 g/mol |  |
| Ranunculin (RAN) inhibited the incorporation of 3H-labeled precursors into DNA and RNA of L1210 cells. RAN (15 mumol/L) markedly decreased DNA synthesis catalyzed by D...more Number of Targets: 0 |
| T3D1709 | Ranelic acid 5459-90-4 | C7H9ClO4 192.597 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D0114 | Radon-222 14859-67-7 | Rn 222.018 g/mol |  |
| The ionizing radiation produced by radon causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal chang...more Number of Targets: 1 |
| T3D0130 | Radon-220 22481-48-7 | Rn 220.011 g/mol |  |
| The ionizing radiation produced by radon causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal chang...more Number of Targets: 1 |
| T3D0105 | Radon 10043-92-2 | Rn 222.000 g/mol |  |
| The ionizing radiation produced by radon causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal chang...more Number of Targets: 1 |
| T3D0106 | Radium-228 15262-20-1 | Ra 228.031 g/mol |  |
| Ionizing radiation produced by radium damages the DNA, resulting in gene mutations and chromosomal aberrations. This can both initiate and promote carcinogenesis, and ...more Number of Targets: 1 |
| T3D0100 | Radium-226 13982-63-3 | Ra 226.025 g/mol |  |
| Ionizing radiation produced by radium damages the DNA, resulting in gene mutations and chromosomal aberrations. This can both initiate and promote carcinogenesis, and ...more Number of Targets: 1 |
| T3D1749 | Radium bromide 10031-23-9 | BrRa 305.904 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 7 |
| T3D3919 | Quizalofop-ethyl 76578-14-8 | C19H17ClN2O4 372.802 g/mol |  |
| Not Available Number of Targets: 1 |